• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults.

作者信息

Amstadter A B, Sumner J A, Acierno R, Ruggiero K J, Koenen K C, Kilpatrick D G, Galea S, Gelernter J

机构信息

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

出版信息

Mol Psychiatry. 2013 Nov;18(11):1148-9. doi: 10.1038/mp.2012.189. Epub 2013 Jan 15.

DOI:10.1038/mp.2012.189
PMID:23319003
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3977702/
Abstract
摘要

相似文献

1
Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults.在一项针对遭受飓风影响的成年人的基于人群的研究中，支持RORA变异与创伤后应激症状之间的关联。
Mol Psychiatry. 2013 Nov;18(11):1148-9. doi: 10.1038/mp.2012.189. Epub 2013 Jan 15.
2
No association between RORA polymorphisms and PTSD in two independent samples.在两个独立样本中，RORA基因多态性与创伤后应激障碍之间无关联。
Mol Psychiatry. 2014 Oct;19(10):1056-7. doi: 10.1038/mp.2014.19. Epub 2014 Jul 22.
3
A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.一项创伤后应激障碍的全基因组关联研究确定了视黄酸相关孤儿受体α（RORA）基因作为一个重要的风险基因座。
Mol Psychiatry. 2013 Aug;18(8):937-42. doi: 10.1038/mp.2012.113. Epub 2012 Aug 7.
4
Support for the association between RORA gene polymorphisms and the DSM-5 posttraumatic stress disorder symptoms in male earthquake survivors in China.中国男性地震幸存者中RORA基因多态性与《精神疾病诊断与统计手册》第5版创伤后应激障碍症状之间关联的证据支持。
Asian J Psychiatr. 2017 Feb;25:138-141. doi: 10.1016/j.ajp.2016.10.028. Epub 2016 Nov 3.
5
RORA and posttraumatic stress trajectories: main effects and interactions with childhood physical abuse history.RORA与创伤后应激轨迹：主要效应以及与童年期身体虐待史的相互作用
Brain Behav. 2015 Apr;5(4):e00323. doi: 10.1002/brb3.323. Epub 2015 Mar 8.
6
RORA rs8042149 polymorphism moderates the association between PTSD symptom severity and transverse temporal gyrus thickness in Han Chinese adults who lost their only child.RORA rs8042149 多态性调节了汉族独生子女丧亲成年人 PTSD 症状严重程度与横颞回厚度之间的关联。
J Affect Disord. 2022 Oct 1;314:318-324. doi: 10.1016/j.jad.2022.07.044. Epub 2022 Jul 22.
7
Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy.伏隔核中 DNMT3a 和 RORA 的减少在创伤后应激障碍样行为中起因果作用：组合表观遗传学治疗的逆转。
Mol Psychiatry. 2021 Dec;26(12):7481-7497. doi: 10.1038/s41380-021-01178-y. Epub 2021 Jul 12.
8
Genetic variants in RORA are associated with asthma and allergy markers in an admixed population.RORA 基因变异与混合人群中的哮喘和过敏标志物相关。
Cytokine. 2019 Jan;113:177-184. doi: 10.1016/j.cyto.2018.07.004. Epub 2018 Jul 7.
9
RAR-related orphan receptor A: One gene with multiple functions related to migraine.RAR 相关孤儿受体 A：一个基因与偏头痛的多种功能相关。
CNS Neurosci Ther. 2020 Dec;26(12):1315-1321. doi: 10.1111/cns.13453. Epub 2020 Sep 5.
10
RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.RORA基因rs12912233和rs880626多态性及其与SCN1A rs3812718的相互作用与癫痫风险的关系：马来西亚的一项病例对照研究
Genomics. 2015 Apr;105(4):229-36. doi: 10.1016/j.ygeno.2015.02.001. Epub 2015 Feb 7.

引用本文的文献

1
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.国际基础与临床药理学联盟第十三分会：核受体超家族-2023 更新。
Pharmacol Rev. 2023 Nov;75(6):1233-1318. doi: 10.1124/pharmrev.121.000436. Epub 2023 Aug 16.
2
Circadian rhythms in the blood-brain barrier: impact on neurological disorders and stress responses.血液-脑屏障的昼夜节律：对神经紊乱和应激反应的影响。
Mol Brain. 2023 Jan 12;16(1):5. doi: 10.1186/s13041-023-00997-0.
3
Classification for psychiatric disorders including schizophrenia, bipolar disorder, and major depressive disorder using machine learning.使用机器学习对包括精神分裂症、双相情感障碍和重度抑郁症在内的精神疾病进行分类。
Comput Struct Biotechnol J. 2022 Sep 12;20:5054-5064. doi: 10.1016/j.csbj.2022.09.014. eCollection 2022.
4
Sleep, circadian system and traumatic stress.睡眠、昼夜节律系统与创伤应激。
Eur J Psychotraumatol. 2021 Sep 28;12(1):1956746. doi: 10.1080/20008198.2021.1956746. eCollection 2021.
5
Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy.伏隔核中 DNMT3a 和 RORA 的减少在创伤后应激障碍样行为中起因果作用：组合表观遗传学治疗的逆转。
Mol Psychiatry. 2021 Dec;26(12):7481-7497. doi: 10.1038/s41380-021-01178-y. Epub 2021 Jul 12.
6
Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression.创伤后外周转录组学、基因组学和相互作用组学的整合确定了创伤后应激障碍和重度抑郁症症状的因果基因。
Mol Psychiatry. 2021 Jul;26(7):3077-3092. doi: 10.1038/s41380-021-01084-3. Epub 2021 May 7.
7
Traumatic stress and the circadian system: neurobiology, timing and treatment of posttraumatic chronodisruption.创伤应激与昼夜节律系统：创伤后昼夜节律紊乱的神经生物学、时机与治疗
Eur J Psychotraumatol. 2020 Nov 27;11(1):1833644. doi: 10.1080/20008198.2020.1833644.
8
Neurophysiology and Psychopathology Underlying PTSD and Recent Insights into the PTSD Therapies-A Comprehensive Review.创伤后应激障碍的神经生理学与精神病理学基础以及创伤后应激障碍治疗的最新见解——综述
J Clin Med. 2020 Sep 12;9(9):2951. doi: 10.3390/jcm9092951.
9
Genetic and Neuroimaging Approaches to Understanding Post-Traumatic Stress Disorder.从遗传学和神经影像学角度理解创伤后应激障碍
Int J Mol Sci. 2020 Jun 24;21(12):4503. doi: 10.3390/ijms21124503.
10
Multilevel Interactions of Stress and Circadian System: Implications for Traumatic Stress.压力与昼夜节律系统的多级相互作用：对创伤性应激的影响
Front Psychiatry. 2020 Jan 28;10:1003. doi: 10.3389/fpsyt.2019.01003. eCollection 2019.

本文引用的文献

1
A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.一项创伤后应激障碍的全基因组关联研究确定了视黄酸相关孤儿受体α（RORA）基因作为一个重要的风险基因座。
Mol Psychiatry. 2013 Aug;18(8):937-42. doi: 10.1038/mp.2012.113. Epub 2012 Aug 7.
2
Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression.低风险创伤、高风险创伤、创伤后应激障碍和重度抑郁症的常见遗传贡献。
Arch Gen Psychiatry. 2012 Mar;69(3):293-9. doi: 10.1001/archgenpsychiatry.2011.1385.
3
Sex hormones in autism: androgens and estrogens differentially and reciprocally regulate RORA, a novel candidate gene for autism.自闭症中的性激素：雄激素和雌激素差异且相互调节 RORA，自闭症的一个新候选基因。
PLoS One. 2011 Feb 16;6(2):e17116. doi: 10.1371/journal.pone.0017116.
4
Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies.创伤后应激障碍的遗传学：全基因组关联研究的综述及建议。
Curr Psychiatry Rep. 2010 Aug;12(4):313-26. doi: 10.1007/s11920-010-0126-6.
5
A genomewide association study of citalopram response in major depressive disorder.一项关于西酞普兰治疗重度抑郁症反应的全基因组关联研究。
Biol Psychiatry. 2010 Jan 15;67(2):133-8. doi: 10.1016/j.biopsych.2009.08.029.
6
Variant in RGS2 moderates posttraumatic stress symptoms following potentially traumatic event exposure.RGS2基因变异可减轻潜在创伤事件暴露后的创伤后应激症状。
J Anxiety Disord. 2009 Apr;23(3):369-73. doi: 10.1016/j.janxdis.2008.12.005. Epub 2008 Dec 25.
7
Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.双相情感障碍全基因组关联数据的趋同功能基因组学：候选基因、通路和机制的全面鉴定
Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):155-81. doi: 10.1002/ajmg.b.30887.
8
Genome-wide association scan of attention deficit hyperactivity disorder.注意缺陷多动障碍的全基因组关联扫描
Am J Med Genet B Neuropsychiatr Genet. 2008 Dec 5;147B(8):1337-44. doi: 10.1002/ajmg.b.30866.
9
Risk and protective factors for psychopathology among older versus younger adults after the 2004 Florida hurricanes.2004年佛罗里达飓风过后，老年人与年轻人心理病理学的风险及保护因素。
Am J Geriatr Psychiatry. 2006 Dec;14(12):1051-9. doi: 10.1097/01.JGP.0000221327.97904.b0. Epub 2006 Oct 11.
10
Social context and the psychobiology of posttraumatic stress.社会环境与创伤后应激障碍的心理生物学
Ann N Y Acad Sci. 2006 Jul;1071:231-41. doi: 10.1196/annals.1364.018.