Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults.
作者信息
Amstadter A B, Sumner J A, Acierno R, Ruggiero K J, Koenen K C, Kilpatrick D G, Galea S, Gelernter J
机构信息
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.
出版信息
Mol Psychiatry. 2013 Nov;18(11):1148-9. doi: 10.1038/mp.2012.189. Epub 2013 Jan 15.
Abstract
摘要
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Support for association of RORA variant and post traumatic stress symptoms in a population-based study of hurricane exposed adults.在一项针对遭受飓风影响的成年人的基于人群的研究中，支持RORA变异与创伤后应激症状之间的关联。
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A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.一项创伤后应激障碍的全基因组关联研究确定了视黄酸相关孤儿受体α（RORA）基因作为一个重要的风险基因座。
Mol Psychiatry. 2013 Aug;18(8):937-42. doi: 10.1038/mp.2012.113. Epub 2012 Aug 7.
2
Common heritable contributions to low-risk trauma, high-risk trauma, posttraumatic stress disorder, and major depression.低风险创伤、高风险创伤、创伤后应激障碍和重度抑郁症的常见遗传贡献。
Arch Gen Psychiatry. 2012 Mar;69(3):293-9. doi: 10.1001/archgenpsychiatry.2011.1385.
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Sex hormones in autism: androgens and estrogens differentially and reciprocally regulate RORA, a novel candidate gene for autism.自闭症中的性激素：雄激素和雌激素差异且相互调节 RORA，自闭症的一个新候选基因。
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