Hernández-Hernández Valeria, Niklas Karl J, Newman Stuart A, Benítez Mariana
Centro de Ciencias de la Complejidad, C3, Universidad Nacional Autónoma de México, Mexico.
Int J Dev Biol. 2012;56(9):661-74. doi: 10.1387/ijdb.120027mb.
Broad comparative studies at the level of developmental processes are necessary to fully understand the evolution of development and phenotypes. The concept of dynamical patterning modules (DPMs) provides a framework for studying developmental processes in the context of wide comparative analyses. DPMs are defined as sets of ancient, conserved gene products and molecular networks, in conjunction with the physical morphogenetic and patterning processes they mobilize in the context of multicellularity. The theoretical framework based on DPMs originally postulated that each module generates a key morphological motif of the basic animal body plans and organ forms. Here, we use a previous definition of the plant multicellular body plan and describe the basic DPMs underlying the main features of plant development. For each DPM, we identify characteristic molecules and molecular networks, and when possible, the physical processes they mobilize. We then briefly review the phyletic distribution of these molecules across the various plant lineages. Although many of the basic plant DPMs are significantly different from those of animals, the framework established by a DPM perspective on plant development is essential for comparative analyses aiming to provide a truly mechanistic explanation for organic development across all plant and animal lineages.
在发育过程层面进行广泛的比较研究对于全面理解发育和表型的进化是必要的。动态模式模块（DPMs）的概念为在广泛比较分析的背景下研究发育过程提供了一个框架。DPMs被定义为一组古老的、保守的基因产物和分子网络，以及它们在多细胞环境中所调动的物理形态发生和模式形成过程。基于DPMs的理论框架最初假定每个模块产生基本动物身体结构和器官形式的关键形态基序。在这里，我们使用植物多细胞身体结构的先前定义，并描述植物发育主要特征背后的基本DPMs。对于每个DPM，我们识别其特征分子和分子网络，并在可能的情况下，识别它们所调动的物理过程。然后，我们简要回顾这些分子在不同植物谱系中的系统分布。尽管许多基本的植物DPMs与动物的有显著不同，但从DPM角度建立的关于植物发育的框架对于旨在为所有植物和动物谱系的有机发育提供真正机制解释的比较分析至关重要。
