Haileamlak Abraham, Muluneh Ayalew T, Alemseged Fessahaye, Tessema Fasil, Woldemichael Kifle, Asefa Makonnen, Mamo Yoseph, Tamiru Solomon, Abebe Gemeda
Department of Pediatrics and Child Health, College of Public Health and Medical Sciences, Jimma University.
Ethiop J Health Sci. 2012 Aug;22(S):39-50.
Health and disease can only be distinguished by accurate and reliable reference values of a particular laboratory test. In interpreting laboratory test results, usually the reported values are compared with established reference values from developed countries. Now it is a fact that there is considerable variation in hematology reference intervals by several variables. However, such data at a population level are scanty in the Ethiopian situation. Therefore, this study was conducted to determine the hematological and immunological values in a community setting.
A population-based cross-sectional study was conducted in Gilgel Gibe Field Research Center (GGFRC) from late September 2008 to end of January 2009. A tsample of 1,965 individuals was included in the study. Blood sample was collected by vacutainer tube and transported to Jimma University Specialized Hospital laboratory. Data were entered in to EpiData and analyzed using SPSS for Windows version 16.0 and STATA 11.
A total of 1965 (955 men and 1010 women) individuals were studied. The mean red blood cell count for men and women was 4.55 × 10(12)/L and 4.34 × 10(12)/L (95 percentile range between 2.9 and 5.7 × 10(12)/L) and 4.34 ×10(12)/L (95 percentile range between 2.8 and 5.2 × 10(12)/L), respectively. On the other hand, the red blood cell count of 95% of the men and women lied between 2.9-5.7 × 10(12) cells/L and 2.8-5.2 × 10(12) cells /L, respectively. The mean hemoglobin value for men was 13.6 gm/dl and for women 12.7 gm/dl. The mean corpuscular volume for men and women was 90.2 fl and 90.8 fl, respectively. The mean platelet value for men was 229.1 ×10(9) cells/L and for women 241.3 ×10(9) cells/L. The mean white blood cells count for men and women was 6.08 ×10(9) cells/L and 6.12 ×10(9) cells/L, respectively. The mean CD4 value was 809 cell/µl for men and 868 cell /µl for women. Forty two percent of the study participants had O blood group.
The hematologic and immunologic profile of the studied population in Southwest Ethiopia is different from the reports from other countries and the standards described in western literature. We recommend conducting similar nationwide study to determine the immunological and hematological reference values of the Ethiopian population as a whole.
健康与疾病只能通过特定实验室检测的准确可靠参考值来区分。在解读实验室检测结果时，通常会将报告值与发达国家既定的参考值进行比较。事实上，血液学参考区间会因多个变量而存在相当大的差异。然而，在埃塞俄比亚的情况下，此类人群层面的数据却很匮乏。因此，本研究旨在确定社区环境中的血液学和免疫学值。
2008年9月下旬至2009年1月底，在吉尔吉尔吉贝田间研究中心（GGFRC）开展了一项基于人群的横断面研究。该研究纳入了1965名个体的样本。通过真空采血管采集血样，并运送至吉姆马大学专科医院实验室。数据录入EpiData，并使用SPSS for Windows 16.0版和STATA 11进行分析。
共研究了1965名个体（955名男性和1010名女性）。男性和女性的平均红细胞计数分别为4.55×10¹²/L和4.34×10¹²/L（95%百分位数范围在2.9至5.7×10¹²/L之间）以及4.34×10¹²/L（95%百分位数范围在2.8至5.2×10¹²/L之间）。另一方面，95%的男性和女性的红细胞计数分别介于2.9 - 5.7×10¹²个细胞/L和2.8 - 5.2×10¹²个细胞/L之间。男性的平均血红蛋白值为13.6克/分升，女性为12.7克/分升。男性和女性的平均红细胞体积分别为90.2飞升和90.8飞升。男性的平均血小板值为229.1×10⁹个细胞/L，女性为241.3×10⁹个细胞/L。男性和女性的平均白细胞计数分别为6.08×10⁹个细胞/L和6.12×10⁹个细胞/L。男性的平均CD4值为809个细胞/微升，女性为868个细胞/微升。42%的研究参与者为O型血。
埃塞俄比亚西南部研究人群的血液学和免疫学特征不同于其他国家的报告以及西方文献中描述的标准。我们建议开展类似的全国性研究，以确定全体埃塞俄比亚人群的免疫学和血液学参考值。
