Ogier J A, Scholler M, Leproivre Y, Pini A, Sommer P, Klein J P
Unité INSERM U 157 Faculté de Chirurgie Dentaire, Strasbourg, France.
FEMS Microbiol Lett. 1990 Mar 1;56(1-2):223-7. doi: 10.1016/0378-1097(90)90155-j.
The nucleotide sequence encoding the SR protein of Streptococcus mutans OMZ 175 (serotype f) has been determined. The sr gene consists of 4667 bp and codes for a 171177 Da protein. Comparison of the inferred amino acid sequence with the one of PAc antigen from S. mutans MT 8148 (serotype c) indicates a 88% conservation of amino acid residues which reflects the close relatedness of both proteins. Major differences in amino acid composition are located at the C-terminal part of the sequence where only 298 amino acids of the terminal 420 are conserved.
变形链球菌OMZ 175（血清型f）编码SR蛋白的核苷酸序列已被确定。sr基因由4667个碱基对组成，编码一种171177道尔顿的蛋白质。将推导的氨基酸序列与变形链球菌MT 8148（血清型c）的PAc抗原的氨基酸序列进行比较，结果表明氨基酸残基的保守率为88%，这反映了两种蛋白质的密切相关性。氨基酸组成的主要差异位于序列的C末端部分，在末端420个氨基酸中只有298个氨基酸是保守的。
