Rossi B, Siciliano G, Risaliti R, Muratorio A
Istituto di Clinica Neurologica dell'Università di Pisa.
Ital J Neurol Sci. 1990 Feb;11(1):37-42. doi: 10.1007/BF02334903.
Six patients with Steinert disease were treated with selenium and vitamin E, for a 24 month period, including a first phase of 12 months, 6 months wash-out interval and a second treatment phase of 6 months. Mean segmental strength values showed significant improvement during the first 12 months of therapy, while marked reductions of serum enzymes CPK, SGOT, SGPT and gamma-GT were observed in some patients. The results support the hypothesis that selenium may play a role in the development of muscle damage in Steinert disease.
六名患有斯坦纳特病的患者接受了为期24个月的硒和维生素E治疗，包括为期12个月的第一阶段、6个月的洗脱期和为期6个月的第二治疗阶段。平均节段肌力值在治疗的前12个月有显著改善，而部分患者的血清酶CPK、SGOT、SGPT和γ-GT明显降低。这些结果支持了硒可能在斯坦纳特病肌肉损伤发展中起作用这一假说。
