PET/CT Center, Anhui Provincial Hospital, Affiliated Provincial Hospital of Anhui Medical University, Hefei 23001, Anhui Province, China.
World J Gastroenterol. 2012 Dec 28;18(48):7409-12. doi: 10.3748/wjg.v18.i48.7409.
Primary hepatic lymphoma is extremely rare, and only a few cases have been described on positron emission tomography (PET) or PET/computed tomography (PET/CT) imaging in the English literature. We report a case of a 55-year-old woman who presented with low-grade fever and weight loss of three months. On CT scanning, a mass was identified which appeared to be a hypoattenuating lesion, on ultrasonographic imaging, the mass was hypoechoic, therefore, liver abscess or hepatic metastasis from a gastrointestinal primary was initially suspected. Tumor markers such as alpha-fetoprotein, carcinoembryonic antigen and carbohydrate antigen 19-9 were within normal limits. PET/CT demonstrated a large abnormal ring-like hypermetabolic focus in the right liver lobe. The lesion was resected and the histopathological findings were consistent with lymphoma. The patient was discharged two weeks after surgery and did not receive any further treatment. After 25 mo follow-up, she is in good health. (18)F-fluorodeoxyglucose PET/CT is useful in confirming the diagnosis of primary hepatic lymphoma by demonstrating no other foci with high uptake in other parts of the body.
原发性肝淋巴瘤非常罕见,仅在少数英文文献中描述了其在正电子发射断层扫描(PET)或 PET/计算机断层扫描(PET/CT)成像上的表现。我们报告了 1 例 55 岁女性,因低热和体重减轻 3 个月就诊。CT 扫描发现 1 个肿块,呈低衰减病变;超声检查示肿块呈低回声,因此最初怀疑为肝脓肿或胃肠道原发性肿瘤的肝转移。甲胎蛋白、癌胚抗原和糖类抗原 19-9 等肿瘤标志物均在正常范围内。PET/CT 显示右肝叶有 1 个大的异常环形高代谢病灶。行病灶切除术,组织病理学检查结果符合淋巴瘤。术后 2 周患者出院,未接受进一步治疗。随访 25 个月后,患者健康状况良好。18F-氟脱氧葡萄糖 PET/CT 通过显示全身其他部位无摄取高的其他病灶,有助于确诊原发性肝淋巴瘤。