Catt K J, Harwood J P, Aguilera G, Dufau M L
Nature. 1979 Jul 12;280(5718):109-16. doi: 10.1038/280109a0.
Regulation of plasma membrane receptors for peptide hormones by the prevailing ligand concentration often causes altered target cell function. Receptor number is determined by hormone-induced changes in membrane conformation, irreversible ligand binding, and processing of ligand-receptor complexes during hormone action.
肽类激素的质膜受体受当前配体浓度的调节，这常常会导致靶细胞功能改变。受体数量由激素诱导的膜构象变化、不可逆的配体结合以及激素作用过程中配体-受体复合物的加工过程所决定。
