用于提高骨水泥界面断裂韧性的微纳级氧化镁颗粒。
Micro and nano MgO particles for the improvement of fracture toughness of bone-cement interfaces.
机构信息
Department of Engineering & Physics, University of Central Oklahoma, Edmond, OK 73034, USA.
出版信息
J Biomech. 2013 Mar 15;46(5):1035-9. doi: 10.1016/j.jbiomech.2012.12.006. Epub 2013 Jan 16.
Abstract
The objective of this study was to determine whether inclusion of magnesium oxide (MgO) in micro and nanoparticulate forms in poly methyl methacrylate (PMMA) cement has any influence on the fracture toughness of bone-cement interfaces. An interfacial fracture mechanics technique was used to compare the values of fracture toughness (KIC) among bone-PMMA, bone-PMMA with micro MgO particles and bone-PMMA with nano MgO particles interfaces. This study found that the values of KIC of bone-PMMA with micro MgO particles and bone-PMMA with nano MgO particles interfaces were significantly higher when compared to the values of KIC of the bone-PMMA interface (p<0.0001). Results indicated that the addition of the micro and nano MgO particles to PMMA improved the quality of bone-cement union.
摘要
本研究旨在确定氧化镁（MgO）以微纳米颗粒形式加入聚甲基丙烯酸甲酯（PMMA）骨水泥中是否会影响骨-骨水泥界面的断裂韧性。本研究采用界面断裂力学技术比较了骨-PMMA、骨-PMMA 中添加微米 MgO 颗粒以及骨-PMMA 中添加纳米 MgO 颗粒界面的断裂韧性（KIC）值。结果表明，与骨-PMMA 界面的 KIC 值相比，骨-PMMA 中添加微米 MgO 颗粒和纳米 MgO 颗粒界面的 KIC 值显著更高（p<0.0001）。结果表明，将微纳米 MgO 颗粒添加到 PMMA 中可提高骨-骨水泥结合的质量。
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