Department of Obstetrics and Gynaecology, KK Women's and Children's Hospital, Singapore.
Singapore Med J. 2013 Jan;54(1):e21-3. doi: 10.11622/smedj.2013021.
A 30-year-old single woman presented with an incidental finding of abdominal mass associated with severe constipation. Her cancer antigen-25, alpha-foetoprotein and beta human chorionic gonadotropin levels were normal, but her carcinoembryonic antigen level was raised at 7.6 g/dL. Magnetic resonance imaging showed a 11.4 cm × 8.6 cm × 9.5 cm right ovarian mass with solid and cystic areas. An open right cystectomy was performed. Intraoperatively, she was found to have hirsutism and clitoromegaly. During the operation, there was a right ovarian 10-cm mass, with faecal loading from the caecum to the transverse colon. The uterus, fallopian tubes, left ovary and intraperitoneal survey were normal. Final histology confirmed strumal carcinoid tumour Stage 1A. This case report shows that a strumal carcinoid tumour can present with longstanding constipation as a patient's main complaint and may also be associated with hirsutism.
一位 30 岁单身女性因偶然发现腹部肿块伴严重便秘而就诊。她的癌症抗原 25、甲胎蛋白和β人绒毛膜促性腺激素水平正常,但癌胚抗原水平升高至 7.6 g/dL。磁共振成像显示右侧卵巢有一个 11.4 cm×8.6 cm×9.5 cm 的肿块,有实性和囊性区域。行开腹右侧卵巢囊肿切除术。术中发现患者有多毛症和阴蒂肥大。术中见右侧卵巢 10 cm 大小肿块,从盲肠到横结肠有粪便堆积。子宫、输卵管、左侧卵巢和腹腔探查均正常。最终组织学证实为 1A 期的卵巢甲状腺类癌。本病例报告表明,甲状腺类癌可表现为长期便秘为主要症状,且可能与多毛症有关。