School of Biomedical Sciences, E Floor Medical School, University of Nottingham, Queen's Medical School Campus, Nottingham NG7 2UH, UK.
Br J Nutr. 2013 Sep 14;110(5):934-42. doi: 10.1017/S0007114512005776. Epub 2013 Jan 23.
Previous studies have reported that polydextrose can reduce food intake; however, the optimal dose required to achieve this effect is currently unknown. The present study investigated the effects of consuming a range of doses of polydextrose on appetite and energy intake (EI) using a randomised within-subject, cross-over design. For this purpose, twenty-one participants (n 12 men, n 9 women) consumed an 837 kJ liquid preload containing 0 g (control), 6.3, 12.5 or 25 g polydextrose. Subjective appetite ratings were collected using visual analogue scales and an ad libitum test meal was served 90 min later. Participants recorded EI for the remainder of the day in a food diary. Test meal EI following the control preload (5756 (sem 423) kJ) was significantly higher than following the 6.3 g (5048 (sem 384) kJ), 12.5 g (4722 (sem 384) kJ) and 25 g (4362 (sem 316) kJ) preloads (P< 0.05), and EI following the 6.3 g preload was significantly higher than following the 25 g preload (P< 0.01). There were no differences in self-reported EI during the remainder of the day between the preloads containing the varying doses of polydextrose. Total EI (breakfast+preload+ad libitum test meal+remainder of the day) was significantly higher when the control preload was consumed (12,051 (sem 805) kJ) compared with either the 12.5 g (10,854 (sem 589) kJ) or 25 g (10,658 (sem 506) kJ) preload (P< 0.05). These differences in EI were not accompanied by corresponding differences in subjective appetite ratings. In summary, polydextrose effectively reduces subsequent EI in a dose-dependent manner.
先前的研究报告表明，聚葡萄糖可以减少食物摄入；然而，目前尚不清楚实现这一效果所需的最佳剂量。本研究采用随机、自身交叉设计，研究了摄入不同剂量聚葡萄糖对食欲和能量摄入（EI）的影响。为此，21 名参与者（n=12 名男性，n=9 名女性）摄入了含有 0g（对照）、6.3g、12.5g 或 25g 聚葡萄糖的 837kJ 液体预餐。使用视觉模拟量表收集主观食欲评分，90 分钟后提供随意测试餐。参与者在食物日记中记录了当天剩余时间的 EI。与对照预餐（5756（sem 423）kJ）相比，6.3g（5048（sem 384）kJ）、12.5g（4722（sem 384）kJ）和 25g（4362（sem 316）kJ）预餐后的测试餐 EI 显著升高（P<0.05），6.3g 预餐后的 EI 显著高于 25g 预餐（P<0.01）。在含有不同剂量聚葡萄糖的预餐之间，其余时间的自我报告 EI 没有差异。当摄入对照预餐时，总 EI（早餐+预餐+随意测试餐+其余时间）显著更高（12051（sem 805）kJ），与 12.5g（10854（sem 589）kJ）或 25g（10658（sem 506）kJ）预餐相比（P<0.05）。这些 EI 差异没有伴随着相应的主观食欲评分差异。总之，聚葡萄糖以剂量依赖的方式有效降低随后的 EI。
