Antoniskis D, Larsen R A
Los Angeles County-University of Southern California Medical Center 90033.
Antimicrob Agents Chemother. 1990 Mar;34(3):470-2. doi: 10.1128/AAC.34.3.470.
We report four cases of acute reversible renal failure in patients with acquired immune deficiency syndrome who received both amphotericin B (for systemic mycoses) and pentamidine isethionate (for Pneumocystis carinii pneumonia). The concurrent use of amphotericin B with either inhaled pentamidine or trimethoprim-sulfamethoxazole did not cause significant renal impairment.
我们报告了4例获得性免疫缺陷综合征患者发生急性可逆性肾衰竭的病例,这些患者同时接受了两性霉素B(用于全身性霉菌感染)和乙磺酸盐喷他脒(用于卡氏肺孢子虫肺炎)治疗。两性霉素B与吸入性喷他脒或甲氧苄啶-磺胺甲恶唑同时使用并未导致明显的肾功能损害。