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低强度脉冲超声在牙科领域的应用现状

Current status of low intensity pulsed ultrasound for dental purposes.

作者信息

Rego Emanuel Braga, Takata Takashi, Tanne Kazuo, Tanaka Eiji

机构信息

Department of Oral and Maxillofacial Pathobiology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan ; Department of Orthodontics and Craniofacial Developmental Biology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.

出版信息

Open Dent J. 2012;6:220-5. doi: 10.2174/1874210601206010220. Epub 2012 Dec 28.

DOI:10.2174/1874210601206010220
PMID:23341848
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3547311/
Abstract

Over the past few years, tissue engineering applied to the dental field has achieved relevant results. Tissue engineering can be described by actions taken to improve biological functions. Several methods have been described to enhance cellular performance and low intensity pulsed ultrasound (LIPUS) has shown to play an important role in cell metabolism. The present article provides an overview about the current status of LIPUS as a tissue engineering tool to be used to enhance tooth and periodontal regeneration.

摘要

在过去几年中，应用于牙科领域的组织工程取得了显著成果。组织工程可以通过采取改善生物学功能的行动来描述。已经描述了几种增强细胞性能的方法，而低强度脉冲超声（LIPUS）已显示在细胞代谢中发挥重要作用。本文概述了LIPUS作为一种用于促进牙齿和牙周组织再生的组织工程工具的现状。

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本文引用的文献

1
Ultrasound stimulation attenuates root resorption of rat replanted molars and impairs tumor necrosis factor-α signaling in vitro.超声刺激可减轻大鼠再植磨牙的牙根吸收，并在体外损害肿瘤坏死因子-α信号通路。
J Periodontal Res. 2011 Dec;46(6):648-54. doi: 10.1111/j.1600-0765.2011.01384.x. Epub 2011 Jun 6.
2
The effects of low-intensity pulsed ultrasound exposure on gingival cells.低强度脉冲超声辐射对牙龈细胞的影响。
J Periodontol. 2011 Oct;82(10):1498-503. doi: 10.1902/jop.2011.100627. Epub 2011 Feb 22.
3
Effects of near-field ultrasound stimulation on new bone formation and osseointegration of dental titanium implants in vitro and in vivo.近场超声刺激对体外和体内牙科钛种植体新骨形成和骨整合的影响。
Ultrasound Med Biol. 2011 Mar;37(3):403-16. doi: 10.1016/j.ultrasmedbio.2010.12.004. Epub 2011 Jan 26.
4
Ultrasound stimulation induces PGE(2) synthesis promoting cementoblastic differentiation through EP2/EP4 receptor pathway.超声刺激通过 EP2/EP4 受体途径诱导 PGE（2）合成，促进成骨细胞分化。
Ultrasound Med Biol. 2010 Jun;36(6):907-15. doi: 10.1016/j.ultrasmedbio.2010.03.008. Epub 2010 May 5.
5
Application of ultrasound in periodontics: Part II.超声在牙周病学中的应用：第二部分。
J Indian Soc Periodontol. 2008 Sep;12(3):55-61. doi: 10.4103/0972-124X.44096.
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Effect of low-intensity pulsed ultrasound on scaffold-free ectopic bone formation in skeletal muscle.低强度脉冲超声对骨骼肌无支架异位骨形成的影响。
Ups J Med Sci. 2009;114(4):242-8. doi: 10.3109/03009730903226659.
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J Appl Oral Sci. 2009 Sep-Oct;17(5):481-6. doi: 10.1590/s1678-77572009000500024.
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Periodontal gene transfer by ultrasound and nano/microbubbles.超声与纳米/微泡介导的牙周基因转移
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Anabolic effects of low-intensity pulsed ultrasound on human gingival fibroblasts.低强度脉冲超声波对人牙龈成纤维细胞的合成代谢作用。
Arch Oral Biol. 2009 Aug;54(8):743-8. doi: 10.1016/j.archoralbio.2009.04.012. Epub 2009 Jun 3.
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Osteoinduction by microbubble-enhanced transcutaneous sonoporation of human bone morphogenetic protein-2.通过微泡增强经皮超声穿孔递送人骨形态发生蛋白-2实现骨诱导
J Gene Med. 2009 Jul;11(7):633-41. doi: 10.1002/jgm.1331.