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采用 RSA 和 DXA 对短股骨颈保留(CFP)干进行前瞻性队列研究。在 27 例患者中随访 2 年,仅观察到初始稳定性,而不能预防近端骨丢失。

A prospective cohort study on the short collum femoris-preserving (CFP) stem using RSA and DXA. Primary stability but no prevention of proximal bone loss in 27 patients followed for 2 years.

机构信息

Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden.

出版信息

Acta Orthop. 2013 Feb;84(1):32-9. doi: 10.3109/17453674.2013.765623. Epub 2013 Jan 23.

Abstract

BACKGROUND AND PURPOSE

Short femoral stems have been introduced in total hip arthroplasty in order to save proximal bone stock. We hypothesized that a short stem preserves periprosthetic bone mineral density (BMD) and provides good primary stability.

METHODS

We carried out a prospective cohort study of 30 patients receiving the collum femoris-preserving (CFP) stem. Preoperative total hip BMD and postoperative periprosthetic BMD in Gruen zones 1-7 were investigated by dual-energy x-ray absorptiometry (DXA), stem migration was analyzed by radiostereometric analysis (RSA), and the Harris hip score (HHS) was determined.

RESULTS

2 patients were excluded intraoperatively and 1 patient was revised due to a deep infection, leaving 27 patients for analysis. The mean HHS increased from 49 (24-79) preoperatively to 99 (92-100) after 2 years. DXA after 1 year showed substantial loss of BMD in Gruen zone 7 (-31%), zone 6 (-19%), and zone 2 (-13%, p < 0.001) compared to baseline BMD determined immediately postoperatively. The bone loss in these regions did not recover after 2 years, whereas the more moderate bone loss in Gruen zones 1, 3, and 5 partially recovered. There was a correlation between low preoperative total hip BMD and a higher amount of bone loss in Gruen zones 2, 6 and 7. RSA showed minor micromotion of the stem: mean subsidence was 0.13 (95% CI: -0.28 to 0.01) mm and mean rotation around the longitudinal axis was 0.01º (95% CI: -0.1 to 0.39) after 2 years.

INTERPRETATION

We conclude that substantial loss in proximal periprosthetic BMD cannot be prevented by the use of a novel type of short, curved stem, and forces appear to be transmitted distally. However, the stems showed very small migration-a characteristic of stable uncemented implants.

摘要

背景与目的

为了节省股骨近端骨量,全髋关节置换术中引入了短柄。我们假设短柄能保留假体周围骨密度(BMD)并提供良好的初始稳定性。

方法

我们进行了一项前瞻性队列研究,纳入了 30 例接受股骨颈保留(CFP)柄的患者。使用双能 X 线吸收法(DXA)检测术前全髋关节 BMD 和术后 Gruen 区域 1-7 假体周围 BMD,通过放射立体分析法(RSA)分析柄的迁移情况,并测定 Harris 髋关节评分(HHS)。

结果

2 例患者术中被排除,1 例因深部感染而翻修,最终有 27 例患者纳入分析。HHS 从术前的 49(24-79)分增加到术后 2 年的 99(92-100)分。术后 1 年 DXA 显示与术后即刻的基线 BMD 相比,Gruen 区域 7(-31%)、区域 6(-19%)和区域 2(-13%,p < 0.001)有大量的 BMD 丢失。这些区域的骨丢失在 2 年内没有恢复,而Gruen 区域 1、3 和 5 中更中度的骨丢失部分恢复。术前全髋关节 BMD 较低与 Gruen 区域 2、6 和 7 中更多的骨丢失相关。RSA 显示柄的微小微动:术后 2 年平均下沉 0.13(95%CI:-0.28 至 0.01)mm,平均绕纵轴旋转 0.01º(95%CI:-0.1 至 0.39)。

结论

新型短弯柄并不能防止假体周围近端 BMD 的大量丢失,而且力似乎是向远端传递的。然而,这些柄的迁移非常小,这是稳定的非骨水泥植入物的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cfc/3584599/10a7203debd3/ORT-84-32-g001.jpg

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