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寻找缺失的数百万病例——慢性阻塞性肺疾病(COPD)本地强化服务对当前及预计诊断率的影响:一项基于人群患病率的中断时间序列分析研究

Finding the missing millions - the impact of a locally enhanced service for COPD on current and projected rates of diagnosis: a population-based prevalence study using interrupted time series analysis.

作者信息

Falzon Christine, Soljak Michael, Elkin Sarah L, Blake Iain D, Hopkinson Nicholas S

机构信息

Central London Community Healthcare, 64 Victoria Street, Westminster, London, UK.

出版信息

Prim Care Respir J. 2013 Mar;22(1):59-63. doi: 10.4104/pcrj.2013.00008.

Abstract

BACKGROUND

Many patients with chronic obstructive pulmonary disease (COPD) are not identified until their condition is relatively advanced and there is a considerable gap between the modelled and diagnosed prevalence of the disease. We have previously shown that, in the first year after the introduction of a locally enhanced service (LES) for COPD in 2008, there was a significant step-up in the diagnosed prevalence.

AIMS

To investigate whether this initial increase in prevalence was sustained, and the impact of this increase on future projected rates of COPD diagnosis.

METHODS

Using data from 2005-2011, we compared the prevalence of diagnosed COPD in the LES Primary Care Trust (LES-PCT) before and after it was introduced. Data were compared with a neighbouring PCT, the London Strategic Health Authority, and England. The true prevalence of COPD was estimated based on data from the Health Survey for England. Trends were extrapolated to estimate the proportion of patients that would be diagnosed in 2017.

RESULTS

The introduction of the LES was associated with a significant acceleration in the annual increase in diagnosed COPD (p<0.0001). By 2011 the prevalence was 1.17% in the LES-PCT compared with a predicted value of 0.91% (95% CI 0.86% to 0.95%) based on the pre-LES trend. There was no change in the rate of increase in COPD prevalence for the neighbouring PCT or for London as a whole. The LES-PCT would be expected to diagnose 55.6% of COPD patients by 2017 compared with only 27.3% without the LES, and only 33.3% would be diagnosed in the neighbouring PCT.

CONCLUSIONS

These data suggest that, with appropriate incentives, it is possible to achieve a sustained improvement in COPD case-finding in primary care and that such policies need to be implemented systematically.

摘要

背景

许多慢性阻塞性肺疾病(COPD)患者直到病情相对严重时才被确诊,该疾病的模型患病率与诊断患病率之间存在相当大的差距。我们之前已经表明,在2008年引入针对COPD的局部强化服务(LES)后的第一年,确诊患病率有了显著提高。

目的

调查这种患病率的初步上升是否持续,以及这种上升对未来预计的COPD诊断率的影响。

方法

利用2005 - 2011年的数据,我们比较了引入LES前后LES初级保健信托基金(LES - PCT)中确诊COPD的患病率。数据与邻近的初级保健信托基金(PCT)、伦敦战略健康管理局以及英格兰的数据进行了比较。基于英格兰健康调查的数据估计了COPD的真实患病率。外推趋势以估计2017年将被诊断出的患者比例。

结果

LES的引入与确诊COPD的年增长率显著加快相关(p<0.0001)。到2011年,LES - PCT中的患病率为1.17%,而根据LES前的趋势预测值为0.91%(95%可信区间0.86%至0.95%)。邻近的PCT或整个伦敦的COPD患病率增长率没有变化。预计到2017年,LES - PCT将诊断出55.6%的COPD患者,而没有LES时仅为27.3%,邻近的PCT中只有33.3%会被诊断出来。

结论

这些数据表明,通过适当的激励措施,有可能在初级保健中持续改善COPD的病例发现情况,并且此类政策需要系统地实施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/377d/6442776/d7ff63cb9ea2/pcrj20138-f1.jpg

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