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由犁头霉引起的再生障碍性贫血患者侵袭性鼻窦眶部真菌病。

Invasive sino-orbital mycosis in an aplastic anemia patient caused by Neosartorya laciniosa.

机构信息

Department of Laboratory Medicine and Pathology, Division of Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada.

出版信息

J Clin Microbiol. 2013 Apr;51(4):1316-9. doi: 10.1128/JCM.02919-12. Epub 2013 Jan 23.

DOI:10.1128/JCM.02919-12
PMID:23345294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3666822/
Abstract

We report the first case of Neosartorya laciniosa invasive sinusitis involving the orbit in an immunocompromised male with aplastic anemia. Treatment included surgical debridement with enucleation of the eye and combination voriconazole and micafungin therapy followed by voriconazole alone. The fungus was identified using sequencing of partial benA and calmodulin genes.

摘要

我们报告了首例免疫功能低下的再生障碍性贫血男性患者发生曲霉菌属犁头霉感染性鼻窦眶部侵袭，该患者接受了手术清创和眼球摘除术，并联合伏立康唑和米卡芬净治疗，随后单独使用伏立康唑。通过部分 benA 和钙调蛋白基因测序鉴定了该真菌。

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本文引用的文献

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Med Mycol. 2012 Aug;50(6):631-6. doi: 10.3109/13693786.2011.639036. Epub 2011 Dec 13.
2
Invasive aspergillosis of orbit in immunocompetent patients: treatment and outcome.免疫功能正常患者的眼眶侵袭性曲霉菌病：治疗与结局。
Ophthalmology. 2011 Sep;118(9):1886-91. doi: 10.1016/j.ophtha.2011.01.059. Epub 2011 Jun 12.
3
Uncommon Neosartorya udagawae fungus as a causative agent of severe corneal infection.罕见的乌达卡那霉素真菌是一种严重角膜感染的致病因子。
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4
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Vet J. 2012 Jan;191(1):58-64. doi: 10.1016/j.tvjl.2011.02.009. Epub 2011 Mar 8.
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Sequential opportunistic infections in two German Shepherd dogs.两只德国牧羊犬的相继机会性感染。
Aust Vet J. 2011 Jan;89(1-2):9-14. doi: 10.1111/j.1751-0813.2010.00666.x.
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J Med Microbiol. 2010 Jul;59(Pt 7):862-865. doi: 10.1099/jmm.0.019133-0. Epub 2010 Apr 15.
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