蛋白质的冷变性和热变性
Cold and warm denaturation of proteins.
作者信息
Caldarelli G, De Los Rios P
机构信息
INFM Sezione di Roma1 and Dipartimento di Fisica, Università `La Sapienza', P.le A. Moro 2, 00185 Roma, Italy.
出版信息
J Biol Phys. 2001 Jun;27(2-3):229-41. doi: 10.1023/A:1013145009949.
Abstract
We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using thismodel we are able to recover both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins.
摘要
我们引入了一个简化的蛋白质模型，其中水的自由度被明确体现出来（尽管是以一种极其简化的方式）。使用这个模型，我们能够在单一框架内重现蛋白质的热变性和冷变性，同时解决有关模型蛋白质结构的重要问题。
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