DNA中的缓慢弛豫过程。
Slow relaxation process in DNA.
作者信息
Sokolov A P, Grimm H, Kisliuk A, Dianoux A J
出版信息
J Biol Phys. 2001 Dec;27(4):313-27. doi: 10.1023/A:1014228824104.
Abstract
A dynamic transition at temperatures ∼200-230K is observed in manyhydrated bio-polymers. It shows up as a sharp increase of the mean-squaredatomic displacements above this temperature range. We present neutronscattering data of DNA at different levels of hydration. The analysis showsthat the dynamic transition in DNA is related to a slow relaxation processin the MHz-GHz frequency range. This slow relaxation process iscompletely suppressed in the dry DNA sample where no dynamic transitionwas observed. The nature of the slow process is discussed. We ascribe it toa global relaxation of DNA molecule that involves cooperative motion ofmany base-pairs and backbone.
摘要
在许多水合生物聚合物中观察到温度约为200 - 230K时的动态转变。它表现为在该温度范围以上原子位移平方平均值的急剧增加。我们展示了不同水合水平下DNA的中子散射数据。分析表明，DNA中的动态转变与兆赫 - 吉赫频率范围内的缓慢弛豫过程有关。在未观察到动态转变的干燥DNA样品中，这种缓慢弛豫过程被完全抑制。讨论了该缓慢过程的性质。我们将其归因于DNA分子的整体弛豫，这涉及许多碱基对和主链的协同运动。
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