基于同步加速器的生物显微光谱学：从中红外到远红外波段
Synchrotron-based Biological Microspectroscopy: From the Mid-Infrared through the Far-Infrared Regimes.
作者信息
Miller L M, Smith G D, Carr G L
机构信息
Brookhaven National Laboratory, National Synchrotron Light Source, Upton, NY 11973 USA.
出版信息
J Biol Phys. 2003 Jun;29(2-3):219-30. doi: 10.1023/A:1024401027599.
Abstract
Infrared radiation from synchrotron storagerings serves as a high-brightness source fordiffraction-limited microspectroscopy inboth the mid- and far-infrared spectralranges. Mid-infrared absorption, due to localvibrational modes within complex molecules,is shown to be sensitive to small chemicalchanges associated with certain diseases.Farinfrared modes are believed to result from thefolding or twisting of larger, morecomplex molecules. The ability for thesynchrotron source to perform microscopy ata frequency of 1 THz is demonstrated.
摘要
同步加速器储存环发出的红外辐射可作为中红外和远红外光谱范围内衍射极限显微光谱的高亮度光源。由于复杂分子内部的局部振动模式，中红外吸收对与某些疾病相关的微小化学变化很敏感。远红外模式被认为是由更大、更复杂分子的折叠或扭曲产生的。文中展示了同步加速器源在1太赫兹频率下进行显微镜观察的能力。
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