空卵泡综合征
Empty follicle syndrome.
作者信息
Kim Jee Hyun, Jee Byung Chul
机构信息
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seongnam, Korea.
出版信息
Clin Exp Reprod Med. 2012 Dec;39(4):132-7. doi: 10.5653/cerm.2012.39.4.132. Epub 2012 Dec 31.
Abstract
Empty follicle syndrome (EFS) is a condition in which no oocytes are retrieved after an apparently adequate ovarian response to stimulation and meticulous follicular aspiration. EFS can be classified into 'genuine' and 'false' types according to hCG levels. It is a rare condition of obscure etiology. The existence of genuine EFS has been questioned and is still controversial. The limitation around EFS is that the definition of EFS is obscure. Management of patients with EFS is a challenge to physicians. No single treatment is known to be universally effective. However, patients should be adequately informed regarding the importance of correct hCG administration because improper hCG administration is a common and preventable cause of EFS. EFS is a syndrome that deserves additional study because such investigation could lead to a further understanding of ovarian biology and infertility.
摘要
空卵泡综合征（EFS）是一种在卵巢对刺激有明显充分反应且进行了细致的卵泡抽吸后仍未获取到卵母细胞的病症。根据人绒毛膜促性腺激素（hCG）水平，EFS可分为“真性”和“假性”类型。它是一种病因不明的罕见病症。真性EFS的存在一直受到质疑且仍存在争议。EFS的局限性在于其定义尚不明确。对EFS患者的管理对医生来说是一项挑战。目前尚无一种治疗方法被认为普遍有效。然而，应让患者充分了解正确注射hCG的重要性，因为不当注射hCG是EFS常见且可预防的原因。EFS是一种值得进一步研究的综合征，因为此类研究可能会加深对卵巢生物学和不孕症的理解。
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Fertil Steril. 2012 Sep;98(3):671-4. doi: 10.1016/j.fertnstert.2012.05.050. Epub 2012 Jul 4.
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Empty follicle syndrome after GnRHa triggering versus hCG triggering in COS.促性腺激素释放激素激动剂触发与绒毛膜促性腺激素触发在控制性卵巢刺激中对空卵泡综合征的影响。
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Empty follicle syndrome--does repeat administration of hCG really work?空卵泡综合征——重复给予 hCG 真的有效吗？
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