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裂谷热与动物源性疾病防控研究与开发的新模式。

Rift Valley fever and a new paradigm of research and development for zoonotic disease control.

机构信息

London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Emerg Infect Dis. 2013 Feb;19(2):189-93. doi: 10.3201/eid1902.120941.

Abstract

Although Rift Valley fever is a disease that, through its wider societal effects, disproportionately affects vulnerable communities with poor resilience to economic and environmental challenge, Rift Valley fever virus has since its discovery in 1931 been neglected by major global donors and disease control programs. We describe recent outbreaks affecting humans and animals and discuss the serious socioeconomic effects on the communities affected and the slow pace of development of new vaccines. We also discuss the mixed global response, which has largely been fueled by the classification of the virus as a potential bioterrorism agent and its potential to migrate beyond its traditional eastern African boundaries. We argue for a refocus of strategy with increased global collaboration and a greater sense of urgency and investment that focuses on an equity-based approach in which funding and research are prioritized by need, inspired by principles of equity and social justice.

摘要

裂谷热是一种疾病,由于其更广泛的社会影响,对经济和环境挑战抵御能力差的弱势社区造成不成比例的影响,但自 1931 年发现以来,裂谷热病毒一直被主要的全球捐助者和疾病控制项目所忽视。我们描述了最近影响人类和动物的疫情,并讨论了对受影响社区的严重社会经济影响,以及新疫苗开发的缓慢步伐。我们还讨论了全球应对措施的混合情况,这在很大程度上是由于该病毒被归类为潜在的生物恐怖主义制剂,以及它有可能超出其传统的东非边界迁移。我们主张重新调整战略,加强全球合作,增强紧迫感和投资,以公平为基础的方法为重点,根据需要优先考虑资金和研究,这一方法的灵感来自公平和社会正义原则。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8a1/3559053/887b6205351e/12-0941-F.jpg

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