Facultad de Ingeniería Electrónica y Biomédica, Universidad Antonio Nariño, Bogotá, Colombia.
Physiol Meas. 2013 Feb;34(2):179-87. doi: 10.1088/0967-3334/34/2/179. Epub 2013 Jan 25.
This work presents the evaluation of pulse rate variability (PRV) obtained from pulse onsets of photoplethysmographic (PPG) signals. Three published algorithms were used to determine the pulse onsets: diastolic point, maximum second derivative and tangent intersection. Temporal series of pulse onsets were obtained for each method, and several variability indices were derived from these series. Simultaneous ECG and PPG records were acquired from 37 healthy volunteers to evaluate the interchangeability between PRV indices and heart rate variability (HRV) indices by the Bland-Altman method. Furthermore, the concordance correlation coefficient was used to correlate the indices. In all the cases, PRV indices obtained through the tangent intersection method showed better accuracy and precision (Bland-Altman analysis, bias ± 1.96 standard deviation: low frequency, LF(ms)(2) = -28.06 ± 72.68; high frequency, HF(ms)(2) = -68.23 ± 192.85; high frequency in normalized units, HF(nu) =-2.02 ± 7.08; LF/HF = 0.17 ± 0.71) and higher correlation (concordance correlation coefficients: low frequency, LF(ms)(2) = 0.99; high frequency, HF(ms)(2) = 0.98; high frequency in normalized units, HF(nu) = 0.97; LF/HF = 0.90) with HRV indices than other methods, and could be used as a good surrogate of HRV.
本工作评估了从光体积描记图（PPG）信号的脉搏起点获得的脉搏率变异性（PRV）。使用了三种已发表的算法来确定脉搏起点：舒张点、最大二阶导数和切线交点。为每种方法获得了脉搏起点的时间序列，并从这些序列中得出了几个可变性指数。从 37 名健康志愿者同时获取 ECG 和 PPG 记录，使用 Bland-Altman 方法评估 PRV 指数与心率变异性（HRV）指数之间的可互换性。此外，还使用了 concordance 相关系数来关联这些指数。在所有情况下，通过切线交点方法获得的 PRV 指数显示出更好的准确性和精密度（Bland-Altman 分析，偏差 ± 1.96 标准差：低频，LF(ms)(2)=-28.06 ± 72.68；高频，HF(ms)(2)=-68.23 ± 192.85；高频归一化单位，HF(nu)=-2.02 ± 7.08；LF/HF=0.17 ± 0.71），与 HRV 指数的相关性更高（ concordance 相关系数：低频，LF(ms)(2)=0.99；高频，HF(ms)(2)=0.98；高频归一化单位，HF(nu)=0.97；LF/HF=0.90），可作为 HRV 的良好替代指标。
