Department of Neurology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareily Road, Lucknow, 226014, India.
Infection. 2013 Jun;41(3):727-9. doi: 10.1007/s15010-013-0406-2. Epub 2013 Jan 29.
Chikungunya virus was initially thought to be a non-neurotropic virus, but recently neurological complications have been reported in patients with chikungunya virus infection. Here, we report a rare case of stimulus-sensitive myoclonus following chikungunya meningoencephalitis. The cranial MRI scan of the patient was normal, the cerebrospinal fluid contained 200 lymphocytes/mm(3), and the serum immunoglobulin M ELISA was positive for chikungunya. The patient improved completely after 1 month of treatment. This case study illustrates that chikungunya virus should also be considered in a febrile patient with myoclonus, especially in an endemic area.
基孔肯雅热病毒最初被认为是非神经嗜性病毒,但最近有报道称,基孔肯雅热病毒感染患者出现了神经并发症。在此,我们报告一例罕见的基孔肯雅热脑膜脑炎后应激敏感肌阵挛病例。患者的头颅 MRI 扫描正常,脑脊液中有 200 个淋巴细胞/mm(3),血清免疫球蛋白 M ELISA 对基孔肯雅热病毒呈阳性。患者在治疗 1 个月后完全康复。该病例研究表明,对于出现肌阵挛的发热患者,特别是在流行地区,也应考虑基孔肯雅热病毒。