Department of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.
Am J Trop Med Hyg. 2011 Aug;85(2):386-9. doi: 10.4269/ajtmh.2011.10-0725.
There has been a recent increase in reports of neurologic complications as major causes of morbidity and mortality in chikungunya virus infection. As a part of 2004-2009 global outbreaks, an unprecedented large chikungunya epidemic occurred in Southern Thailand during 2008-2009 in which 49,069 cases were reported. During this period, we encountered two patients with meningoencephalitis and another patient with myeloneuropathy among 1,018 cases diagnosed as chikungunya in our hospital. The clinical pictures are presented and the key points are used to recognize and differentiate chikungunya from Japanese encephalitis virus, dengue virus, and herpesvirus infections, which are more common causes of meningoencephalitis and myelitis in this region.
近来，寨卡病毒感染的主要并发症——神经系统并发症，导致发病率和死亡率上升。作为 2004-2009 年全球疫情的一部分，2008-2009 年泰国南部发生了前所未有的大规模寨卡病毒疫情，报告病例 49069 例。在此期间，我院共诊断 1018 例寨卡病毒感染患者，其中有 2 例患者为脑膜脑炎，1 例患者为脊神经根炎。本文呈现了这 3 例患者的临床图片，并重点介绍了如何识别和区分寨卡病毒与日本脑炎病毒、登革热病毒和疱疹病毒感染，这些病毒是该地区更常见的脑膜脑炎和脊髓炎病因。
