Department of Psychiatry, University of Calgary, Calgary, Alberta, Canada.
Clin EEG Neurosci. 2013 Apr;44(2):95-104. doi: 10.1177/1550059412465607. Epub 2013 Jan 24.
Although dysfunctional anger is not a Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition, Text Revision [DSM-IV-TR]) diagnosis, it sometimes presents as a primary clinical complaint and as a comorbid feature in a subset of adults with attention-deficit/hyperactivity disorder (ADHD). No known studies have examined electroencephalographic (EEG) profiles in adults with comorbid dysfunctional anger and ADHD (ADHD + anger). Resting EEG was recorded in 14 ADHD + anger adults (11 males) and 14 controls. Relative power was assessed at standard frequencies, as was frontal absolute α power asymmetry. A modest increase was noted in β1 power in the ADHD + anger group. Unexpectedly, relatively decreased left (or increased right) frontocortical activity (α assessed) was noted in the ADHD + anger group, which was also characterized by a more diffuse θ/β ratio scalp distribution. Nonmedicated ADHD + anger adults exhibited modest resting cortical hyperarousal, consistent with the findings in a subset of children with ADHD characterized by anger-associated problems. The unexpected frontal α asymmetry may reflect enhanced activity of frontal inhibitory mechanisms.
尽管功能失调性愤怒不是《精神障碍诊断与统计手册》（第四版，文本修订版[DSM-IV-TR]）的诊断，但它有时表现为主要的临床主诉，并且在注意力缺陷/多动障碍（ADHD）的亚组成年人中作为合并特征出现。目前尚无研究检查合并功能失调性愤怒和 ADHD（ADHD +愤怒）的成年人的脑电图（EEG）图谱。在 14 名 ADHD +愤怒的成年人（11 名男性）和 14 名对照者中记录了静息脑电图。评估了标准频率下的相对功率，以及额绝对α功率不对称。在 ADHD +愤怒组中注意到β1 功率略有增加。出乎意料的是，在 ADHD +愤怒组中观察到相对减少的左侧（或增加的右侧）额叶皮质活动（评估的α），其特征还在于θ/β 比率头皮分布更加弥散。未经药物治疗的 ADHD +愤怒的成年人表现出适度的静息皮质过度唤醒，这与具有愤怒相关问题的 ADHD 儿童亚组的发现一致。意外的额叶α不对称可能反映了额叶抑制机制的增强活动。
