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瑞香狼毒中黄酮四糖苷和苯甲醇糖苷

Flavone tetraglycosides and benzyl alcohol glycosides from the Mongolian medicinal plant Dracocephalum ruyschiana.

机构信息

Department of Pharmacognosy, Tohoku Pharmaceutical University , 4-4-1 Komatsushima, Aoba-ku, Sendai, Japan.

出版信息

J Nat Prod. 2013 Feb 22;76(2):186-93. doi: 10.1021/np300609u. Epub 2013 Jan 28.

Abstract

From an extract of the aerial parts of Dracocephalum ruyschiana, five new flavone tetraglycosides, five new benzyl alcohol glycosides, and 19 known compounds were isolated. The tetraglycosides contain a 7-O-β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl-(1→2)-[α-l-rhamnopyranosyl-(1→6)]-β-d-glucopyranosyl moiety. The benzyl alcohol glycosides had acyl groups on their glycosyl or aglycone moieties. The compounds were tested for antioxidant activity using DPPH. Although the new compounds were not active, phenylpropanoylquinic acid derivatives were revealed as radical scavengers in D. ruyschiana.

摘要

从罗勒属植物的地上部分提取得到五个新的黄酮四糖苷、五个新的苯甲醇糖苷和 19 个已知化合物。四糖苷含有 7-O-β-d-吡喃葡萄糖基-(1→2)-β-d-吡喃葡萄糖基-(1→2)-[α-l-鼠李吡喃糖基-(1→6)]-β-d-吡喃葡萄糖基部分。苯甲醇糖苷的糖基或糖苷配基上有酰基。这些化合物用 DPPH 进行了抗氧化活性测试。虽然新化合物没有活性,但苯丙酰基奎宁酸衍生物被证明是罗勒属植物中的自由基清除剂。

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