Department of Pathology, the 208th Hospital of PLA, Changchun 130062, China.
Chin J Cancer Res. 2012 Jun;24(2):164-6. doi: 10.1007/s11670-012-0164-1.
Extraskeletal osteosarcoma (EOS) is rare and commonly arises in the retroperitoneum, limbs, head and neck. There is no significant difference between EOS and other malignant tumors in soft tissue. Localized pain and swelling are the common presenting symptoms. Clinical diagnosis of EOS is difficult, imaging techniques may be helpful and careful, and the histopathological analysis is necessary. The common histological variants of EOS include: osteoblastoma, chondroblastoma, and fibroblastoma, and other unusual subtypes were reported occasionally. It should be distinguished with myositis ossificans, malignant mesenchymoma, giant cell tumor and parosteal osteosarcoma. We present an EOS arising in the penis. The primary site and histological category of the tumor were extremely rare. We hope the case will be helpful to the recognition of clinical signs, iconography and histopathology of EOS.
骨外骨肉瘤(EOS)罕见,常见于腹膜后、四肢、头颈部。EOS 与软组织中的其他恶性肿瘤无明显差异。局部疼痛和肿胀是常见的表现症状。EOS 的临床诊断较难,影像学技术可能有帮助,且需要仔细的组织病理学分析。EOS 的常见组织学变异型包括:成骨细胞瘤、成软骨细胞瘤和成纤维细胞瘤,偶尔也会有其他不常见的亚型报道。需要与骨化性肌炎、恶性间叶瘤、巨细胞瘤和骨旁骨肉瘤相鉴别。我们报告了一例发生于阴茎的 EOS。肿瘤的原发部位和组织学类型极为罕见。我们希望该病例有助于认识 EOS 的临床体征、影像学和组织病理学特征。