Department of Endocrinology, UZ Leuven and KU Leuven, Herestraat 49, 3000 Leuven, Belgium.
Int J Endocrinol. 2013;2013:248121. doi: 10.1155/2013/248121. Epub 2013 Jan 10.
Aims. This paper aims to evaluate characteristics and pregnancy outcomes in women prior classified normal by Carpenter and Coustan criteria (old criteria) and now gestational diabetes (GDM) by the IADPSG criteria. Methods. Retrospective analysis of 6727 pregnancies is used. Using the old criteria, 222 had GDM (old GDM). Using the IADPSG criteria, 382 had GDM of which 160 had a normal glucose tolerance with the old criteria (new GDM). We compared the new GDM group with the old GDM group and women with normal glucose tolerance with both criteria (NGT group, 6345). Results. New GDM women were younger (31.6 ± 4.7 versus 33.3 ± 7.2 years, P = 0.010) than old GDM women. Caesarean section was performed in 30.5% of new GDM, in 32.4% of old GDM (P = 0.706), and in 23.3% of NGT women (P = 0.001). Large for gestational age occurred in 10.8% of new GDM, in 13.8% of old GDM (P = 0.473), and in 9.0% of NGT women (P = 0.099). Shoulder dystocia occurred in 3.9% of new GDM, in 3.2% of old GDM (P = 0.736), and in 1.4% of NGT women (P = 0.007). Conclusion. Using the IADPSG criteria, more women are identified as having GDM, and these women carry an increased risk for adverse gestational outcome compared to women without GDM.
目的。本文旨在评估根据 Carpenter 和 Coustan 标准(旧标准)被归类为正常的女性和现在根据 IADPSG 标准被诊断为妊娠期糖尿病(GDM)的女性的特征和妊娠结局。
方法。本研究回顾性分析了 6727 例妊娠病例。使用旧标准,有 222 例患有 GDM(旧 GDM)。使用 IADPSG 标准,有 382 例患有 GDM,其中 160 例在旧标准下糖耐量正常(新 GDM)。我们将新 GDM 组与旧 GDM 组和两种标准下糖耐量正常的女性(NGT 组,6345 例)进行比较。
结果。新 GDM 女性的年龄比旧 GDM 女性小(31.6 ± 4.7 岁 vs. 33.3 ± 7.2 岁,P = 0.010)。新 GDM 患者行剖宫产术的比例为 30.5%,旧 GDM 患者为 32.4%(P = 0.706),NGT 患者为 23.3%(P = 0.001)。巨大儿的发生率在新 GDM 患者中为 10.8%,在旧 GDM 患者中为 13.8%(P = 0.473),在 NGT 患者中为 9.0%(P = 0.099)。肩难产的发生率在新 GDM 患者中为 3.9%,在旧 GDM 患者中为 3.2%(P = 0.736),在 NGT 患者中为 1.4%(P = 0.007)。
结论。使用 IADPSG 标准,更多的女性被诊断为患有 GDM,与无 GDM 的女性相比,这些女性的不良妊娠结局风险增加。