Nikitin E V, Pak S G
Ter Arkh. 1990;62(2):76-9.
As many as 160 patients with acute virus hepatitis B (AVHB) were examined over time. Spectroscopy was used to study the activity of glucose-6-phosphate dehydrogenase (G-6-PDH), glutathione peroxidase-1 (GP1), glutathione peroxidase-2 (GP2), glutathione reductase (GR), glutathione transferase (GT) and to measure the concentration of reduced glutathione (GSH) in the blood serum and in red blood cells. Within the first days of the icteric period, the activity of all the enzymes rose, followed by reduction of the activity of G-6-PDH, GP1, GP2, GR and the concentration of GSH at the height of the disease. The GT activity remained high throughout the entire disease period.
对多达160例急性乙型病毒性肝炎（AVHB）患者进行了长期检查。采用光谱法研究葡萄糖-6-磷酸脱氢酶（G-6-PDH）、谷胱甘肽过氧化物酶-1（GP1）、谷胱甘肽过氧化物酶-2（GP2）、谷胱甘肽还原酶（GR）、谷胱甘肽转移酶（GT）的活性，并测定血清和红细胞中还原型谷胱甘肽（GSH）的浓度。在黄疸期的最初几天内，所有酶的活性均升高，随后在疾病高峰期G-6-PDH、GP1、GP2、GR的活性及GSH浓度降低。GT活性在整个疾病期间均保持较高水平。
