Infectious Disease and Immunogenetics Section (IDIS), Department of Transfusion Medicine, Clinical Center and Center for Human Immunology (CHI), NIH, Bethesda MD, USA.
Clin Transl Med. 2012 Aug 14;1(1):15. doi: 10.1186/2001-1326-1-15.
Supported by the International Society for Translational Medicine (ISTM), Wenzhou Medical College and the First Affiliated Hospital of Wenzhou Medical College, the International Conference on Translational Medicine (ICTM) was held on October 22-23, 2011 in Wenzhou, China. Nearly 800 registrants attended the meeting, primarily representing institutes and hospitals in Europe, The United States of America, And Asia, and China. The meeting was chaired and organized by Dr. Xiangdong Wang, Xiaoming Chen, Richard Coico, Jeffrey M. Drazen, Richard Horton, Francesco M. Marincola, Laurentiu M. Popescu, Jia Qu and Aamir Shahzad.
The meeting focused on the communication of the need to foster translational medicine (TM) by building and broadening bridges between basic research and clinical studies at the international level. The meeting included distinguished TM experts from academia, the pharmaceutical and diagnostics industries, government agencies, regulators, and clinicians and provided the opportunity to identify shared interests and efforts for collaborative approaches utilizing cutting edge technologies, innovative approaches and novel therapeutic interventions. The meeting defined the concept of TM in its two-way operational scheme and emphasized the need for bed to bench efforts based directly on clinical observation.
It was the meeting participants' realization that the shared main goals of TM include breaking the separation between clinic practice and basic research, establishing positive feedback by understanding the basis of expected and unexpected clinical outcomes and accelerating basic research relevant to human suffering. The primary objectives of the meeting were two-fold: to accelerate the two-way translation by informing the participants representing the different disciplines about the state of art activities around TM approaches; and to identify areas that need to be supported by redirecting limited resources as well as identifying new sources of funding. This report summarizes key concepts presented during the meeting representing the state-of-art translational research and salient aspects of the ensuing discussions.
由国际转化医学学会（ISTM）、温州医科大学和温州医科大学附属第一医院支持，国际转化医学会议（ICTM）于 2011 年 10 月 22 日至 23 日在中国温州举行。近 800 名注册代表参加了会议，主要代表来自欧洲、美国和亚洲的研究所和医院，以及中国。会议由王向东博士、陈晓鸣博士、Richard Coico、Jeffrey M. Drazen、Richard Horton、Francesco M. Marincola、Laurentiu M. Popescu、贾群和 Aamir Shahzad 共同主持和组织。
会议重点是在国际层面上通过建立和拓宽基础研究与临床研究之间的桥梁，传达促进转化医学（TM）的必要性。会议邀请了来自学术界、制药和诊断行业、政府机构、监管机构以及临床医生的杰出转化医学专家，为利用前沿技术、创新方法和新的治疗干预措施进行合作方法提供了机会，以确定共同的利益和努力。会议定义了 TM 的双向操作方案的概念，并强调了需要直接基于临床观察进行从病床到实验室的努力。
会议参与者认识到，TM 的共同主要目标包括打破临床实践和基础研究之间的分离，通过了解预期和意外临床结果的基础来建立积极的反馈，并加速与人类痛苦相关的基础研究。会议的主要目标有两个：一是通过向代表不同学科的参与者通报 TM 方法的最新研究进展，加快双向转化；二是确定需要重新分配有限资源支持的领域，以及确定新的资金来源。本报告总结了会议期间提出的关键概念，这些概念代表了转化研究的最新进展，以及随后讨论的重要方面。
