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拓展转化医学的视角:观察性数据的价值。

Expanding the perspective of translational medicine: the value of observational data.

出版信息

J Transl Med. 2012 Mar 27;10:61. doi: 10.1186/1479-5876-10-61.

DOI:10.1186/1479-5876-10-61
PMID:22452969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3320561/
Abstract

In 2003, the Journal of Translational Medicine was launched to foster the publication of high quality research in both "bench-to-bedside" as well as ex vivo human observation. In spite of the success of several large-scale observational studies, e.g. Framingham Heart Study, the opportunity to expand upon the ex vivo human observation has remained limited within the field of translational medicine. We believe that this presents a significant opportunity that merits consideration in both the planning and analysis of large scale observational studies and can contribute greatly to expanding our approaches in translational medicine.

摘要

2003 年,《转化医学杂志》(Journal of Translational Medicine)创刊,旨在促进“从实验室到病床”以及体外人体观察这两方面高质量研究的发表。尽管弗莱明翰心脏研究(Framingham Heart Study)等几项大规模观察性研究取得了成功,但转化医学领域中,体外人体观察的机会仍然有限。我们认为,这是一个重大的机会,值得在大规模观察性研究的规划和分析中加以考虑,并能极大地促进我们在转化医学中的方法的拓展。

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