耐甲氧西林金黄色葡萄球菌含有 mecC 基因在瑞典奶牛中。
Methicillin-resistant Staphylococcus aureus containing mecC in Swedish dairy cows.
机构信息
Department of Animal Health and Antimicrobial Strategies, National Veterinary Institute, Uppsala, SE-751 89, Sweden.
出版信息
Acta Vet Scand. 2013 Jan 31;55(1):6. doi: 10.1186/1751-0147-55-6.
Abstract
BACKGROUND
Hitherto, methicillin-resistant Staphylococcus aureus (MRSA) has not been detected in Swedish cattle. However, due to the report of mecC, a novel homologue to the mecA gene, there was reason to re-evaluate susceptibility results from strain collections of Staphylococcus aureus and test suspected isolates for the presence of mecC.
FINDINGS
Bovine isolates of S. aureus with elevated minimum inhibitory concentrations of beta-lactams were retrospectively tested for presence of mecC. In four of the isolates mecC was detected.
CONCLUSION
In Sweden, this is the first finding of MRSA in cattle and the first detection of MRSA harbouring mecC of domestic animal origin. MRSA in animal populations has implications as a potential reservoir with risk for spread to humans. Occurrence of MRSA among Swedish cattle appears still very limited.
摘要
背景
迄今为止，瑞典牛群中尚未检出耐甲氧西林金黄色葡萄球菌（MRSA）。然而，由于 mecC 的报告，这是 mecA 基因的一种新型同源物，因此有理由重新评估金黄色葡萄球菌菌株分离物的药敏结果，并检测疑似分离物中 mecC 的存在。
结果
对青霉素类药物最低抑菌浓度升高的牛源金黄色葡萄球菌分离物进行了 mecC 检测。在 4 个分离物中检测到 mecC。
结论
在瑞典，这是首次在牛群中发现 MRSA，也是首次发现携带动物源性 mecC 的 MRSA。动物群体中的 MRSA 作为潜在的传染源，存在向人类传播的风险。在瑞典牛群中，MRSA 的发生似乎仍然非常有限。
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