基于采集权重的化学位移成像可提高 SLOOP 定量检测人心肌磷代谢物的准确性。
Acquisition-weighted chemical shift imaging improves SLOOP quantification of human cardiac phosphorus metabolites.
机构信息
The Intervention Centre, Oslo University Hospital, Oslo, Norway; Institute of Radiology, University of Würzburg, Würzburg, Germany.
Institute of Radiology, University of Würzburg, Würzburg, Germany.
出版信息
Z Med Phys. 2014 Mar;24(1):49-54. doi: 10.1016/j.zemedi.2013.01.002. Epub 2013 Jan 30.
PURPOSE
Phosphorous metabolite ratios in human myocardium were determined by a combination of acquisition weighted CSI and a SLOOP evaluation and the results were compared to corresponding SLOOP experiments using standard CSI.
MATERIALS AND METHODS
10 healthy subjects were examined at 1.5 T using both standard CSI and acquisition weighted CSI. Both experiments were performed with a similar acquisition time and the same spatial resolution. The PCr/ATP ratio was determined and the localization properties of both experiments were compared.
RESULTS
The PCr/ATP ratio of 2.2±0.4 found for the experiment using acquisition weighted CSI was almost identical to the value of 2.0±0.4 for standard CSI. The sensitivity and the localization properties improved in all subjects using SLOOP evaluation of the acquisition weighted sampling in comparison to the standard CSI acquisition with an average of 3% and 18%, respectively.
CONCLUSION
The employment of acquisition weighting allows for a further improvement of the (31)P SLOOP spectroscopy of the human heart.
目的
通过组合采集加权 CSI 和 SLOOP 评估，确定人心脏中的磷代谢物比，并将结果与使用标准 CSI 的相应 SLOOP 实验进行比较。
材料和方法
在 1.5 T 下，使用标准 CSI 和采集加权 CSI 对 10 名健康受试者进行检查。两种实验均具有相似的采集时间和相同的空间分辨率。测定 PCr/ATP 比，并比较两种实验的定位特性。
结果
使用采集加权 CSI 的实验得出的 PCr/ATP 比为 2.2±0.4，几乎与标准 CSI 的 2.0±0.4 值相同。与标准 CSI 采集相比，使用 SLOOP 评估采集加权采样可在所有受试者中提高灵敏度和定位特性，平均分别提高 3%和 18%。
结论
采用采集加权可以进一步提高人心脏的（31）P SLOOP 光谱。
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