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[α-生育酚和游离脂肪酸对大鼠脑突触体脂质基质物理性质及腺苷酸环化酶活性的影响]

[Effects of alpha tocopherol and free fatty acids on physical properties of lipid matrix and adenylate cyclase activity in rat brain synaptosomes].

作者信息

Gorbunov N V, Kuznetsova L A, Brusovanik V I, Erin A N

出版信息

Biull Eksp Biol Med. 1990 Feb;109(2):153-5.

PMID:2337650
Abstract

Using modification of physical state of synaptosome lipid matrix by free fatty acids and alpha-tocopherol it was shown that fluidity of lipid matrix isn't limiting regulating factor for the activity of alpha-adrenergic aden late cyclase. From the point of view that state of annular lipids is different from the state of lipid bilayer in synaptosomes we suggest that composition of annular lipids regulates alpha-adrenergic adenylate cyclase system in rat neuronal membranes.

摘要

通过游离脂肪酸和α-生育酚对突触体脂质基质物理状态的修饰表明,脂质基质的流动性不是α-肾上腺素能腺苷酸环化酶活性的限制调节因子。从环形脂质状态与突触体中脂质双分子层状态不同的角度来看,我们认为环形脂质的组成调节大鼠神经元膜中的α-肾上腺素能腺苷酸环化酶系统。

相似文献

1
[Effects of alpha tocopherol and free fatty acids on physical properties of lipid matrix and adenylate cyclase activity in rat brain synaptosomes].[α-生育酚和游离脂肪酸对大鼠脑突触体脂质基质物理性质及腺苷酸环化酶活性的影响]
Biull Eksp Biol Med. 1990 Feb;109(2):153-5.
2
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