Department of Medical Toxicology, Banner Good Samaritan Medical Center, Phoenix, AZ, USA.
J Med Toxicol. 2013 Jun;9(2):196-8. doi: 10.1007/s13181-013-0287-x.
The phenethylamines, including 2, 5 dimethoxy-4-iodophenethylamine, commonly referred to as 2C-I, have recently emerged as a new class of designer drugs. Cases of toxicity from these drugs are not well described in the literature. This case report describes a 19 year-old male who insufflated 2C-I. Following the ingestion, the patient developed recurrent seizures, and was taken to the emergency department, where he was noted to be hyperadrenergic and had recurrent seizures. The patient was diagnosed with serotonin syndrome and experienced prolonged respiratory failure, although he ultimately made a full recovery. Comprehensive drug testing revealed the presence of 2C-I. The pharmacologic properties of 2C-I are also discussed.
苯乙胺类物质，包括 2,5-二甲氧基-4-碘苯乙胺，通常被称为 2C-I，最近已成为一类新的设计药物。这些药物引起的毒性病例在文献中描述得并不充分。本病例报告描述了一名 19 岁男性患者吸入 2C-I 的情况。摄入后，患者出现反复发作的癫痫发作，并被送往急诊室，在急诊室中，他被发现具有高肾上腺素能状态和反复发作的癫痫发作。该患者被诊断为血清素综合征，并经历了长时间的呼吸衰竭，但最终完全康复。全面的药物检测显示存在 2C-I。还讨论了 2C-I 的药理特性。
