Department of Psychology, Boston University, Boston, MA 02216, USA.
J Clin Psychol. 2013 Jun;69(6):630-45. doi: 10.1002/jclp.21965. Epub 2013 Feb 4.
Intolerance of uncertainty (IU) is a characteristic predominantly associated with generalized anxiety disorder (GAD); however, emerging evidence indicates that IU may be a shared element of emotional disorders.
This study aimed to examine IU across diagnostic categories, change in IU during transdiagnostic treatment, and the relationship between change in IU and treatment outcome.
Patients diagnosed with heterogeneous anxiety and depressive disorders received up to 18 weeks of a transdiagnostic cognitive-behavioral therapy intervention. Patient self-reported IU and self-report and clinician-rated symptom/functioning measures were administered at pretreatment and posttreatment.
When controlling for negative affectivity, IU correlated with measures of depressive symptoms and worry severity at pretreatment. Patients with GAD and panic disorder exhibited the highest pretreatment IU scores, yet IU scores did not differ significantly based on the presence or absence of a specific diagnosis. A significant decrease in IU was observed, and change in IU was related to reduced anxiety and depressive symptom levels at posttreatment across diagnostic categories.
Change in IU can be observed across problem areas in transdiagnostic treatment and such change is correlated with treatment outcome.
对不确定性的容忍度(IU)是主要与广泛性焦虑症(GAD)相关的特征;然而,新出现的证据表明,IU 可能是情绪障碍的共同要素。
本研究旨在检查跨诊断类别的 IU、IU 在跨诊断治疗中的变化,以及 IU 变化与治疗结果之间的关系。
被诊断为异质焦虑和抑郁障碍的患者接受了最多 18 周的跨诊断认知行为治疗干预。在治疗前和治疗后,患者自我报告 IU 以及自我报告和临床医生评定的症状/功能测量。
当控制负性情感时,IU 与治疗前的抑郁症状和担忧严重程度相关。广泛性焦虑症和惊恐障碍患者的 IU 得分最高,但 IU 得分与特定诊断的存在与否无显著差异。在跨诊断治疗中,IU 显著下降,IU 的变化与治疗后焦虑和抑郁症状水平的降低有关。
在跨诊断治疗中可以观察到 IU 在问题领域的变化,这种变化与治疗结果相关。