Fregert S
Section of Occupational Dermatology, University Hospital, Lund, Sweden.
Contact Dermatitis. 1975;1(2):96-107. doi: 10.1111/j.1600-0536.1975.tb05334.x.
This study included 1,752 patients considered to have occupational dermatoses. The most common diagnosis was contact dermatitis. The dermatitis was of an allergic type in three-quarters of men and in half of women. One-fifth of the women with irritant contact dermatitis had an atopic history. Contact dermatitis was localized on the hands in 94% of women and in 84% of men. The most common allergens in men were chromium, rubber and plastic, and in women nickel, rubber and chromium. Chromium allergy occurred in four-fifths of the men in the building, metal and tanning industries. In one-fifth of the women, nickel allergy developed in cleaning work. Rubber allergy developed in the rubber industry in one-fifth of the cases. Half of the women with contact dermatitis were engaged in either nursing or cleaning work. A follow-up 2-3 years after treatment of 555 patients with contact dermatitis was completed by means of questionnaires. The eczema was healed in one-quarter of the patients, one-half had periodic symptoms, and one-quarter had permanent symptoms. The prognosis was the same for those who changed their work or stopped working as it was for those who continued their eczema-inducing work.
本研究纳入了1752名被认为患有职业性皮肤病的患者。最常见的诊断是接触性皮炎。四分之三的男性和一半的女性患的是过敏性皮炎。五分之一患刺激性接触性皮炎的女性有特应性病史。94%的女性和84%的男性接触性皮炎局限于手部。男性最常见的过敏原是铬、橡胶和塑料,女性是镍、橡胶和铬。建筑、金属和制革行业五分之四的男性对铬过敏。五分之一的女性在清洁工作中对镍过敏。五分之一的病例在橡胶行业发生橡胶过敏。一半患接触性皮炎的女性从事护理或清洁工作。通过问卷调查对555例接触性皮炎患者进行了治疗后2至3年的随访。四分之一的患者湿疹痊愈,一半有周期性症状,四分之一有永久性症状。更换工作或停止工作的患者与继续从事诱发湿疹工作的患者预后相同。