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评估腹膜透析患者的疼痛程度和生活质量:一项横断面研究。

Assessing pain levels and quality of life in peritoneal dialysis patients: a cross-sectional study.

作者信息

Bdair Amjad, Tamimi Rami, Shratih Ahmad, Abuhalima Dania, Abdalla Mazen, Sarsour Alaa, Jebreen Kamel, Hamdan Zakaria, Nazzal Zaher

机构信息

Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.

Specialized Surgery Department, An-Najah National University Hospital, Nablus, Palestine.

出版信息

BMC Nephrol. 2025 Mar 27;26(1):155. doi: 10.1186/s12882-025-04083-6.

Abstract

BACKGROUND

End-stage renal disease is a significant global health issue, and Peritoneal Dialysis (PD) is a vital treatment modality. The study aims to assess the Quality of Life (QoL) and pain levels in PD patients and explore potential influencing factors.

METHODS

A cross-sectional study was conducted in 2022 involving 76 PD patients at a referral tertiary dialysis center in Palestine. The study evaluated patient demographics, clinical data, laboratory measures, quality of life as assessed by the KDQOL-SF36, and pain levels as determined by the Brief Pain Inventory. Statistical analyses, including multivariate linear regression, were employed to identify relevant associations.

RESULTS

This study included 76 PD disease patients, with 68.4% being under the age of 60 and 53.9% being male. Almost one-third of the participants (34.0%) reported mild to severe pain, and 23.7% reported low to high interference levels. Pain severity was negatively correlated with supplement doses for both vitamin D3 (p = 0.049) and calcium (p < 0.01). Female patients reported higher pain severity (p = 0.001) and interference (p < 0.007) levels. The study revealed relatively higher QoL among our cohort of PD patients compared to previously published findings in similar settings, specifically for HD populations. Factors such as age, comorbid conditions, and duration of dialysis influenced QoL (p < 0.05). Pain severity and interference were negatively correlated with QoL (p = 0.01).

CONCLUSION

This study provides valuable insights into the QoL and pain experiences of PD patients in Palestine. It underscores the importance of effective pain management strategies and holistic care to improve QoL in this patient population. Addressing psychological and emotional well-being is vital for optimizing treatment adherence and long-term outcomes.

CLINICAL TRIAL NUMBER

Not applicable.

摘要

背景

终末期肾病是一个重大的全球健康问题,腹膜透析(PD)是一种重要的治疗方式。本研究旨在评估PD患者的生活质量(QoL)和疼痛水平,并探索潜在的影响因素。

方法

2022年在巴勒斯坦一家三级转诊透析中心对76例PD患者进行了一项横断面研究。该研究评估了患者的人口统计学特征、临床数据、实验室指标、通过KDQOL-SF36评估的生活质量以及通过简明疼痛量表确定的疼痛水平。采用包括多变量线性回归在内的统计分析来确定相关关联。

结果

本研究纳入了76例PD疾病患者,其中68.4%年龄在60岁以下,53.9%为男性。近三分之一的参与者(34.0%)报告有轻度至重度疼痛,23.7%报告有低至高度的干扰水平。疼痛严重程度与维生素D3(p = 0.049)和钙(p < 0.01)的补充剂量呈负相关。女性患者报告的疼痛严重程度(p = 0.001)和干扰水平(p < 0.007)更高。与之前在类似环境中发表的关于血液透析人群的研究结果相比,本研究显示我们的PD患者队列的生活质量相对较高。年龄、合并症和透析时间等因素影响生活质量(p < 0.05)。疼痛严重程度和干扰与生活质量呈负相关(p = 0.01)。

结论

本研究为巴勒斯坦PD患者的生活质量和疼痛体验提供了有价值的见解。它强调了有效的疼痛管理策略和整体护理对改善该患者群体生活质量的重要性。关注心理和情绪健康对于优化治疗依从性和长期预后至关重要。

临床试验编号

不适用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/94df/11948673/7acdebe5354c/12882_2025_4083_Fig1_HTML.jpg

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