Lee G P, Loring D W, Meader K J, Brooks B B
Section of Neurosurgery, Medical College of Georgia, Augusta 30912-4010.
Brain Cogn. 1990 Mar;12(2):267-80. doi: 10.1016/0278-2626(90)90019-k.
Emotional and behavioral responses to sodium amobarbital injection were examined in 44 epilepsy surgery candidates. Thirty-three emotional reactions occurred in 26 patients, 44% of the reactions following right hemisphere injection and 32% after injection of the left hemisphere. Among all patients examined, laughter/elated mood was statistically more frequent following right hemisphere injection while crying was statistically associated with left hemisphere injections. These observed effects were not related to amobarbital dose, sex, bilateral hemispheric inactivation (angiographic crossflow), general cognitive status, or side of seizure onset. These results support differing specialization of emotional expression in the right and left cerebral hemispheres and their subcortical connections.
对44名癫痫手术候选患者进行了戊巴比妥钠注射后的情绪和行为反应检查。26名患者出现了33种情绪反应，其中44%的反应发生在右半球注射后，32%发生在左半球注射后。在所有接受检查的患者中，右半球注射后出现欢笑/愉悦情绪的情况在统计学上更为常见，而哭泣在统计学上与左半球注射有关。观察到的这些效应与戊巴比妥钠剂量、性别、双侧半球失活（血管造影交叉血流）、一般认知状态或癫痫发作起始侧无关。这些结果支持左右大脑半球及其皮质下连接在情绪表达上存在不同的专业化分工。
