• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

默克尔细胞癌:一种罕见疾病的多学科管理

Merkel cell carcinoma: interdisciplinary management of a rare disease.

作者信息

Schneider Sven, Thurnher Dietmar, Erovic Boban M

机构信息

Department of Otolaryngology-Head and Neck Surgery, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria.

出版信息

J Skin Cancer. 2013;2013:189342. doi: 10.1155/2013/189342. Epub 2013 Jan 14.

DOI:10.1155/2013/189342
PMID:23401779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3557626/
Abstract

Background. The goal of this paper is to review contemporary multidisciplinary treatment with reference to Merkel cell carcinoma. Management of this rare but highly aggressive skin cancer is a complex undertaking that necessitates an understanding of its etiology, epidemiology, clinical presentation, and the coordinated work of several clinical specializations. Recent Findings. The contemporary literature employs a multidisciplinary approach to achieve the best patient's treatment. Conclusion. This paper presents an algorithm for contemporary management for the rare and aggressive Merkel cell carcinoma. Multidisciplinary approach in a tumor center provides high-quality care for patients with Merkel cell carcinoma.

摘要

背景。本文旨在回顾默克尔细胞癌的当代多学科治疗方法。这种罕见但极具侵袭性的皮肤癌的管理是一项复杂的工作,需要了解其病因、流行病学、临床表现以及多个临床专业的协同工作。最新研究结果。当代文献采用多学科方法以实现最佳的患者治疗效果。结论。本文提出了一种针对罕见且侵袭性强的默克尔细胞癌的当代管理算法。肿瘤中心的多学科方法为默克尔细胞癌患者提供高质量护理。

相似文献

1
Merkel cell carcinoma: interdisciplinary management of a rare disease.默克尔细胞癌:一种罕见疾病的多学科管理
J Skin Cancer. 2013;2013:189342. doi: 10.1155/2013/189342. Epub 2013 Jan 14.
2
Updated review of the pathogenesis and management of Merkel cell carcinoma.Merkel 细胞癌发病机制与治疗的最新研究进展综述。
J Cutan Med Surg. 2010 Mar-Apr;14(2):51-61. doi: 10.2310/7750.2010.09017.
3
Merkel cell carcinoma: An algorithm for multidisciplinary management and decision-making.默克尔细胞癌:多学科管理与决策算法
Crit Rev Oncol Hematol. 2016 Feb;98:170-9. doi: 10.1016/j.critrevonc.2015.10.008. Epub 2015 Nov 10.
4
Merkel cell carcinoma: diagnosis, management, and outcomes. Merkel 细胞癌:诊断、治疗和预后。
Plast Reconstr Surg. 2013 May;131(5):771e-778e. doi: 10.1097/PRS.0b013e3182865cf3.
5
A Therapeutic and Diagnostic Multidisciplinary Pathway for Merkel Cell Carcinoma Patients.默克尔细胞癌患者的治疗与诊断多学科路径
Front Oncol. 2020 Apr 15;10:529. doi: 10.3389/fonc.2020.00529. eCollection 2020.
6
Nationwide multidisciplinary consensus on the clinical management of Merkel cell carcinoma: a Delphi panel.全国多学科共识对 Merkel 细胞癌的临床管理:德尔菲小组。
J Immunother Cancer. 2022 Jun;10(6). doi: 10.1136/jitc-2022-004742.
7
A Case Report of Leptomeningeal Carcinomatosis Secondary to Recurrent Merkel Cell Carcinoma after Avelumab.阿维鲁单抗治疗后复发性默克尔细胞癌继发脑膜癌病 1 例报告
Perm J. 2021 May;25. doi: 10.7812/TPP/20.235.
8
Recent advances in the biology of Merkel cell carcinoma.默克尔细胞癌生物学研究的最新进展。
Hum Pathol. 2011 Aug;42(8):1063-77. doi: 10.1016/j.humpath.2011.01.020.
9
Clinical features and treatment of vulvar Merkel cell carcinoma: a systematic review.外阴默克尔细胞癌的临床特征与治疗:一项系统综述
Gynecol Oncol Res Pract. 2017 Jan 25;4:2. doi: 10.1186/s40661-017-0037-x. eCollection 2017.
10
Scientific and clinical developments in Merkel cell carcinoma: A polyomavirus-driven, often-lethal skin cancer.默克尔细胞癌的科学和临床进展:一种由多瘤病毒驱动的、常致命的皮肤癌。
J Dermatol Sci. 2022 Jan;105(1):2-10. doi: 10.1016/j.jdermsci.2021.10.004. Epub 2021 Oct 18.

引用本文的文献

1
Is the Addition of Chemotherapy to Adjuvant Radiation in Merkel Cell Cancer Beneficial? Real-World Data with Long-Term Follow-Up.默克尔细胞癌辅助放疗中添加化疗是否有益?长期随访的真实世界数据。
Cancers (Basel). 2025 Mar 11;17(6):945. doi: 10.3390/cancers17060945.
2
Merkel Cell Carcinoma Treatment in Finland in 1986-2016-A Real-World Data Study.1986 - 2016年芬兰 Merkel 细胞癌治疗——一项真实世界数据研究
Cancers (Basel). 2020 May 13;12(5):1224. doi: 10.3390/cancers12051224.
3
Merkel Cell Carcinoma, Version 1.2018, NCCN Clinical Practice Guidelines in Oncology.

本文引用的文献

1
Merkel cell carcinoma: 30-year experience from a single institution.默克尔细胞癌:单中心 30 年经验。
Ann Surg Oncol. 2013 Apr;20(4):1365-73. doi: 10.1245/s10434-012-2779-3. Epub 2012 Dec 1.
2
The etiology and epidemiology of merkel cell carcinoma.默克尔细胞癌的病因学与流行病学
Curr Probl Cancer. 2010 Jan-Feb;34(1):14-37. doi: 10.1016/j.currproblcancer.2010.01.001.
3
The multidisciplinary tumor conference in gynecologic oncology--does it alter management?妇科肿瘤多学科肿瘤会议——是否改变了治疗方法?
Merkel 细胞癌,1.2018 年版,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2018 Jun;16(6):742-774. doi: 10.6004/jnccn.2018.0055.
4
Merkel cell carcinoma: Epidemiology, pathogenesis, diagnosis and therapy.默克尔细胞癌:流行病学、发病机制、诊断与治疗。
Rev Endocr Metab Disord. 2017 Dec;18(4):517-532. doi: 10.1007/s11154-017-9433-0.
5
Expression of Merkelcell polyomavirus (MCPyV) large T-antigen in Merkel cell carcinoma lymph node metastases predicts poor outcome.默克尔细胞多瘤病毒(MCPyV)大T抗原在默克尔细胞癌淋巴结转移灶中的表达预示着预后不良。
PLoS One. 2017 Aug 1;12(8):e0180426. doi: 10.1371/journal.pone.0180426. eCollection 2017.
6
Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment.头颈部 Merkel 细胞癌:诊断和治疗建议。
Ann Surg Oncol. 2017 Oct;24(11):3430-3437. doi: 10.1245/s10434-017-5993-1. Epub 2017 Jul 31.
7
Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options.头颈部默克尔细胞癌:发病机制、当前及新兴治疗选择
Onco Targets Ther. 2015 Aug 19;8:2157-67. doi: 10.2147/OTT.S72202. eCollection 2015.
8
Incidence of Merkel cell carcinoma in Olmsted County, Minnesota: a population-based study.明尼苏达州奥尔姆斯特德县默克尔细胞癌的发病率:一项基于人群的研究。
Int J Dermatol. 2016 Jan;55(1):e11-5. doi: 10.1111/ijd.12812. Epub 2015 Jul 31.
9
Merkel cell carcinoma: an illustrative case and review.默克尔细胞癌:一个典型病例及综述
Postepy Dermatol Alergol. 2014 Oct;31(5):325-8. doi: 10.5114/pdia.2014.40797. Epub 2014 Oct 22.
10
Merkel cell carcinoma, version 1.2014. Merkel 细胞癌,第 1.2014 版。
J Natl Compr Canc Netw. 2014 Mar 1;12(3):410-24. doi: 10.6004/jnccn.2014.0041.
Int J Gynecol Cancer. 2009 Dec;19(9):1470-2. doi: 10.1111/IGC.0b013e3181bf82df.
4
Incidence of Merkel cell carcinoma in renal transplant recipients.肾移植受者中默克尔细胞癌的发病率。
Nephrol Dial Transplant. 2009 Oct;24(10):3231-5. doi: 10.1093/ndt/gfp334. Epub 2009 Jul 8.
5
Merkel cell carcinoma.默克尔细胞癌
J Natl Compr Canc Netw. 2009 Mar;7(3):322-32. doi: 10.6004/jnccn.2009.0024.
6
Tumor board: more than treatment planning--a 1-year prospective survey.肿瘤多学科会诊:不止于治疗规划——一项为期1年的前瞻性调查
J Cancer Educ. 2008;23(4):235-7. doi: 10.1080/08858190802189014.
7
Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancer.评估单日多学科门诊对胰腺癌管理的影响。
Ann Surg Oncol. 2008 Aug;15(8):2081-8. doi: 10.1245/s10434-008-9929-7. Epub 2008 May 7.
8
Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.195例默克尔细胞癌确诊时的临床特征:AEIOU特征
J Am Acad Dermatol. 2008 Mar;58(3):375-81. doi: 10.1016/j.jaad.2007.11.020.
9
Clonal integration of a polyomavirus in human Merkel cell carcinoma.多瘤病毒在人类默克尔细胞癌中的克隆整合
Science. 2008 Feb 22;319(5866):1096-100. doi: 10.1126/science.1152586. Epub 2008 Jan 17.
10
Understanding high-quality cancer care: a summary of expert perspectives.理解高质量癌症护理:专家观点综述
Cancer. 2008 Feb 15;112(4):934-42. doi: 10.1002/cncr.23250.