Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Forschungszentrum Jülich GmbH, Jülich, Germany.
Neuroimage. 2013 Jun;73:135-43. doi: 10.1016/j.neuroimage.2013.01.070. Epub 2013 Feb 9.
EPI with Keyhole (EPIK) is a hybrid imaging technique used to improve the performance of EPI in dynamic MRI applications. The method had been previously validated at 1.5 T with both phantom and in vivo images; EPIK was able to provide a higher temporal resolution and less image distortions than single-shot EPI. The data presented here demonstrate that the performance of EPIK can be further improved by accelerating it with the parallel imaging. For this work, this combination was tested at 3 T. After initial evaluation using phantom images, use of the method in functional MRI was verified with visual fMRI measurements as well as MRI simulation results. The results showed that accelerated EPIK had increased temporal resolution with favorable robustness against susceptibility artifacts when compared with EPI or non-accelerated EPIK.
EPI 与锁孔（EPIK）是一种混合成像技术，用于提高动态 MRI 应用中 EPI 的性能。该方法先前已在 1.5T 上通过体模和体内图像进行了验证；EPIK 能够提供比单次激发 EPI 更高的时间分辨率和更少的图像失真。这里呈现的数据表明，通过并行成像加速可以进一步提高 EPIK 的性能。在这项工作中，这种组合在 3T 下进行了测试。在使用体模图像进行初步评估后，通过视觉 fMRI 测量以及 MRI 模拟结果验证了该方法在功能 MRI 中的应用。结果表明，与 EPI 或非加速 EPIK 相比，加速 EPIK 具有更高的时间分辨率，并且对磁化率伪影具有更好的稳健性。
