Ito Komei
Department of Allergy, Aichi Children's Health and Medical Center, Aichi 474-8710, Japan.
Asia Pac Allergy. 2013 Jan;3(1):59-69. doi: 10.5415/apallergy.2013.3.1.59. Epub 2013 Jan 22.
A diagnosis of food allergies should be made based on the observation of allergic symptoms following the intake of suspected foods and the presence of allergen-specific IgE antibodies. The oral food challenge (OFC) test is the most reliable clinical procedure for diagnosing food allergies. Specific IgE testing of allergen components as well as classical crude allergen extracts helps to make a more specific diagnosis of food allergies. The Japanese Society of Pediatric Allergy and Clinical Immunology issued the 'Japanese Pediatric Guideline for Food Allergy 2012' to provide information regarding the standardized diagnosis and management of food allergies. This review summarizes recent progress in the diagnosis of food allergies, focusing on the use of specific IgE tests and the OFC procedure in accordance with the Japanese guidelines.
食物过敏的诊断应基于摄入可疑食物后出现的过敏症状以及过敏原特异性IgE抗体的存在。口服食物激发试验（OFC）是诊断食物过敏最可靠的临床方法。对过敏原成分以及经典的粗制过敏原提取物进行特异性IgE检测有助于更准确地诊断食物过敏。日本儿科学过敏与临床免疫学会发布了《2012年日本儿童食物过敏指南》，以提供有关食物过敏标准化诊断和管理的信息。本综述总结了食物过敏诊断的最新进展，重点介绍了根据日本指南使用特异性IgE检测和OFC程序的情况。
