Cambronero J, Arlandis S, Errando C, Mora A M
Servicio de Urología, Hospital Infanta Leonor, Madrid, España.
Actas Urol Esp. 2013 Jul-Aug;37(7):401-7. doi: 10.1016/j.acuro.2012.11.011. Epub 2013 Feb 12.
Following current European Guidelines, Lower Urinary Tract Symptoms (LUTS) are produced by several causes and, thus, thorough clinical assessment should be undertaken for a correct therapeutic management. This study was conducted in order to assess the symptoms profile and their impact on Health-Related Quality of Life (HRQL) of male patients attending urology outpatient clinics.
Epidemiological, cross-sectional study including adult male patients (n=826) presenting with at least one de novo previously untreated LUTS. Socio-demographic and clinical variables were collected. Patients completed IPSS, Bladder Control Self-Assessment Questionnaire (B-SAQ) and SF-12 questionnaires.
Mean age (SD) was 65 (10) years. A combination of storage, voiding and post-micturition symptoms were present in 69% of subjects and 30% showed >2 urgency episodes and >6 micturitions daily (storage symptoms -SS- sub-population). Storage symptoms were the reason for consultation in 86%. Mean peak urinary flow (Q(max)) was 11.4 mL/s, in 44% of patients,prostate volume was 20-40 mL and 91% showed moderate or severe symptoms on IPSS with an overall mean (SD) score of 17 (7). SS sub-population had higher B-SAQ scores (6,9 vs 4,8 for symptoms; 7,8 vs 5,1 for bother), and worse HRQL (IPSS item 8).
These findings support the importance of addressing treatment adequately according to patient profile, bothersomeness and impact on HRQL.
根据当前欧洲指南，下尿路症状（LUTS）由多种原因引起，因此，为了进行正确的治疗管理，应进行全面的临床评估。本研究旨在评估泌尿外科门诊男性患者的症状特征及其对健康相关生活质量（HRQL）的影响。
进行流行病学横断面研究，纳入至少有一项新发且此前未经治疗的LUTS的成年男性患者（n = 826）。收集社会人口统计学和临床变量。患者完成国际前列腺症状评分（IPSS）、膀胱控制自我评估问卷（B-SAQ）和SF-12问卷。
平均年龄（标准差）为65（10）岁。69%的受试者存在储尿、排尿和排尿后症状的组合，30%的受试者每天出现>2次尿急发作和>6次排尿（储尿症状-SS-亚组）。86%的患者因储尿症状前来咨询。平均最大尿流率（Q(max)）为11.4 mL/s，44%的患者前列腺体积为20 - 40 mL，91%的患者在IPSS上表现为中度或重度症状，总体平均（标准差）评分为17（7）。SS亚组的B-SAQ评分更高（症状方面为6.9 vs 4.8；困扰方面为7.8 vs 5.1），HRQL更差（IPSS第8项）。
这些发现支持根据患者特征、困扰程度和对HRQL的影响进行充分治疗的重要性。
