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白皮杉醇,一种有效的生物活性二苯乙烯,作为桃金娘科薄树中的主要酚类成分。

Piceatannol, a potent bioactive stilbene, as major phenolic component in Rhodomyrtus tomentosa.

机构信息

Institut des Sciences de la Vie, UCLouvain, B-1348 Louvain-la-Neuve, Belgium.

出版信息

Food Chem. 2013 Jun 1;138(2-3):1421-30. doi: 10.1016/j.foodchem.2012.10.125. Epub 2012 Nov 10.

DOI:10.1016/j.foodchem.2012.10.125
PMID:23411263
Abstract

The sim fruit (Rhodomyrtus tomentosa) has long been used in folk medicine to treat diarrhoea, dysentery, and to boost the immune system. The purpose of this work was to determine its phenolic profile and to evaluate the changes of content during maturation, as well as the variations induced by environmental conditions. Using HPLC-ESI-HR-MS, 19 phenolic compounds (PCs) were tentatively characterised and included stilbenes and ellagitannins as major components, followed by anthocyanins, flavonols, and gallic acid. PCs were then further quantified by HPLC-DAD. Piceatannol, a promising health-promoting stilbene component, was the major PC in the fruit with a concentration of 2.3mg/g dry weight at full maturity stage. This concentration is 1000-2000 times higher than that of red grapes, a major source of stilbene in the human diet. During maturation, the contents in piceatannol and other stilbenes, ellagitannins, and flavonols decreased while the anthocyanin content increased. Shade-grown sim fruits showed significantly higher piceatannol levels than sun-exposed fruits. Taken together, these findings highlight the potential of sim, an under-utilised plant species from South-East Asia, as a source of health-promoting fruits.

摘要

思茅莓(Rhodomyrtus tomentosa)在民间医学中一直被用于治疗腹泻、痢疾和增强免疫系统。本工作的目的是确定其酚类物质的特征,并评估其在成熟过程中的含量变化,以及环境条件引起的变化。使用 HPLC-ESI-HR-MS,初步鉴定了 19 种酚类化合物(PCs),包括作为主要成分的芪类和鞣花单宁,其次是花色苷、类黄酮和没食子酸。然后通过 HPLC-DAD 进一步定量了 PCs。白藜芦醇是一种有希望的促进健康的芪类成分,是果实中的主要 PC,在完全成熟阶段的浓度为 2.3mg/g 干重。这个浓度是人类饮食中主要的白藜芦醇来源红葡萄的 1000-2000 倍。在成熟过程中,白藜芦醇和其他芪类、鞣花单宁和类黄酮的含量下降,而花色苷的含量增加。遮荫生长的思茅莓果实的白藜芦醇含量明显高于暴露在阳光下的果实。总之,这些发现强调了思茅莓作为一种具有促进健康潜力的水果的潜在价值,思茅莓是东南亚一种未充分利用的植物物种。

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