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新生儿期用于严重先天性心脏病的流量可调式双侧肺动脉环扎术。

Flow-adjustable bilateral pulmonary artery banding in the neonatal period for severe congenital heart diseases.

作者信息

Yoshimoto Akihiro, Miyamoto Takashi, Ozaki Shinichi, Kobayashi Tohru, Kobayashi Tomio

机构信息

Department of Cardiovascular Surgery and Cardiology, Gunma Children's Medical Center, 779, Shimohakoda, Hokkitsu, Shibukawa, Gunma 377-8577, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2013 Jun;61(6):340-4. doi: 10.1007/s11748-013-0221-9. Epub 2013 Feb 19.

DOI:10.1007/s11748-013-0221-9
PMID:23420331
Abstract

OBJECTIVE

We perform bilateral pulmonary artery banding (BPAB) combined with postoperative percutaneous pulmonary artery balloon dilatation (PABD) as stage I palliation for severe congenital heart diseases. The objective of this study was to evaluate the efficacy of our management strategy for the treatment of severe congenital heart diseases.

METHODS

From October 2007 to March 2010, 9 consecutive patients underwent BPAB. Subsequently, all patients had a second-stage operation; we performed biventricular repair for 3 cases and univentricular repair for 6 cases. Clinical data were obtained by retrospectively reviewing medical records.

RESULTS

There was no early mortality (30 days). After the neonatal period, we controlled the pulmonary blood flow to be slightly elevated by PABD. Therefore, the Qp/Qs level was around 1.0, which might contribute to achieving good pulmonary artery growth and avoid intraoperative pulmonary arterioplasty. Except for one patient, intraoperative pulmonary arterioplasty in the second-stage operation was not necessary. Regarding Norwood procedure, an 8 mm RV-PA (right ventricle-pulmonary artery) conduit was available for respective patients.

CONCLUSIONS

Although further studies are warranted, our strategy might prove to be a valid clinical option for the treatment of severe congenital heart diseases.

摘要

目的

我们采用双侧肺动脉环缩术(BPAB)联合术后经皮肺动脉球囊扩张术(PABD)作为重症先天性心脏病的一期姑息治疗方法。本研究的目的是评估我们的治疗策略对重症先天性心脏病的治疗效果。

方法

2007年10月至2010年3月,连续9例患者接受了BPAB。随后,所有患者均接受了二期手术;我们对3例患者进行了双心室修复,对6例患者进行了单心室修复。通过回顾病历获取临床数据。

结果

无早期(30天)死亡病例。在新生儿期后,我们通过PABD将肺血流量控制在略高于正常水平。因此,Qp/Qs水平约为1.0,这可能有助于实现肺动脉的良好生长并避免术中肺动脉成形术。除1例患者外,二期手术中无需进行术中肺动脉成形术。对于诺伍德手术,分别为每位患者准备了一根8毫米的右心室-肺动脉(RV-PA)导管。

结论

尽管有必要进行进一步研究,但我们的策略可能被证明是治疗重症先天性心脏病的一种有效的临床选择。

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本文引用的文献

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Mortality and neurodevelopmental outcome at 1 year of age comparing hybrid and Norwood procedures.比较杂交术与 Norwood 术 1 岁时死亡率和神经发育结局。
Eur J Cardiothorac Surg. 2012 Jul;42(1):33-9. doi: 10.1093/ejcts/ezr286. Epub 2012 Jan 18.
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Staged repair of truncus arteriosus with interrupted aortic arch: adjustable pulmonary artery banding.动脉干和主动脉弓中断的分期修复:可调式肺动脉带缩术。
Ann Thorac Surg. 2010 Mar;89(3):973-5. doi: 10.1016/j.athoracsur.2009.07.044.
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Dilatable pulmonary artery banding in infants with low birth weight or complex congenital heart disease allows avoidance or postponement of subsequent surgery.
可扩张肺动脉带术在低体重儿或复杂先天性心脏病患儿中的应用可避免或推迟后续手术。
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Early results of bilateral pulmonary artery banding for hypoplastic left heart syndrome.左心发育不全综合征的双侧肺动脉环缩术的早期结果。
Eur J Cardiothorac Surg. 2009 Dec;36(6):973-9. doi: 10.1016/j.ejcts.2009.05.009. Epub 2009 Jul 8.
5
Endoluminal pulmonary artery banding: technique, applications and results.腔内肺动脉环扎术:技术、应用及结果
Ann Thorac Surg. 2008 Aug;86(2):588-94;discussion 594-5. doi: 10.1016/j.athoracsur.2008.04.041.
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Changing outcomes of pulmonary artery banding with the percutaneously adjustable pulmonary artery band.
Ann Thorac Surg. 2008 Feb;85(2):593-8. doi: 10.1016/j.athoracsur.2007.07.057.
7
A novel adjustable pulmonary artery banding system for hypoplastic left heart syndrome.一种用于左心发育不全综合征的新型可调式肺动脉束带系统。
Ann Thorac Surg. 2007 Dec;84(6):2081-4. doi: 10.1016/j.athoracsur.2007.05.004.
8
Modification of stage II procedure after hybrid palliation (bilateral pulmonary artery banding and ductal stenting) for hypoplastic left-sided heart syndrome: Modified arch reconstruction with retained stented ductus patch.用于左心发育不全综合征的杂交姑息治疗(双侧肺动脉束带术和动脉导管支架置入术)后II期手术的改良:保留带支架动脉导管补片的改良主动脉弓重建术。
J Thorac Cardiovasc Surg. 2007 Dec;134(6):1588-9. doi: 10.1016/j.jtcvs.2007.08.033.
9
Fate of the "opened" arterial duct: Lessons learned from bilateral pulmonary artery banding for hypoplastic left heart syndrome under the continuous infusion of prostaglandin E1.“开放”动脉导管的转归:持续输注前列腺素E1下行双侧肺动脉环扎术治疗左心发育不全综合征的经验教训
J Thorac Cardiovasc Surg. 2007 Jun;133(6):1653-4. doi: 10.1016/j.jtcvs.2007.01.053.
10
Factors influencing neurologic outcome after neonatal cardiopulmonary bypass: what we can and cannot control.新生儿体外循环后影响神经功能转归的因素:我们能控制与不能控制的因素
Ann Thorac Surg. 2006 Jun;81(6):S2381-8. doi: 10.1016/j.athoracsur.2006.02.074.