用卡介苗对黑色素瘤进行免疫治疗：病灶内注射后出现两例死亡病例。
Immunotherapy of melanoma with BCG: two fatalities following intralesional injection.
作者信息
McKhann C F, Hendrickson C G, Spitler L E, Gunnarsson A, Banerjee D, Nelson W R
出版信息
Cancer. 1975 Feb;35(2):514-20. doi: 10.1002/1097-0142(197502)35:2<514::aid-cncr2820350233>3.0.co;2-f.
Abstract
Two fatalities are reported following intralesional injection of BCG for immunotherapy of malignant melanoma. In both cases the terminal events were characterized by high fevers, major clotting defects, hypotension, and anuria, suggesting that the mechanism was hypersensitivity to BCG.
摘要
据报道，在通过病灶内注射卡介苗进行恶性黑色素瘤免疫治疗后出现了两例死亡病例。在这两例病例中，末期症状均表现为高热、严重凝血功能缺陷、低血压和无尿，提示其机制为对卡介苗过敏。
Zotero 插件