• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

新型环戊烯酮衍生物由稀有放线菌南山链霉菌 NEAU 119 产生。

Novel cyclopentenone derivatives produced by a rare actinobacterial strain Actinoalloteichus nanshanensis sp. nov. NEAU 119.

机构信息

a School of Life Science, Life Science and Biotechnology Research Center, Northeast Agricultural University , Harbin , 150030 , People's Republic of China.

出版信息

Nat Prod Res. 2013 Oct;27(20):1863-9. doi: 10.1080/14786419.2013.771349. Epub 2013 Feb 22.

DOI:10.1080/14786419.2013.771349
PMID:23432091
Abstract

Four novel cyclopentenone derivatives (1-4), characterising a cyclopentenone ring conjugated with a 1,8-dioxadecalin, were isolated from rare actinobacterial strain Actinoalloteichus nanshanensis sp. nov. NEAU 119. The structures of these compounds were elucidated on the basis of extensive spectroscopic analysis. Bioassays indicated that compounds 1-4 showed low cytotoxicities against human leukaemia cell line K562 and human renal carcinoma cell line ACHN. To the best of our knowledge, this is the first example of isolation of C11 cyclopentenones from actinomycetes.

摘要

从稀有放线菌南山不动杆菌新种 Actinoalloteichus nanshanensis sp. nov. NEAU 119 中分离得到四个新型环戊烯酮衍生物（1-4），其特征为环戊烯酮环与 1,8-二氧代癸烷共轭。基于广泛的光谱分析确定了这些化合物的结构。生物测定表明，化合物 1-4 对人白血病细胞系 K562 和人肾癌细胞系 ACHN 的细胞毒性较低。据我们所知，这是首次从放线菌中分离出 C11 环戊烯酮。

相似文献

1
Novel cyclopentenone derivatives produced by a rare actinobacterial strain Actinoalloteichus nanshanensis sp. nov. NEAU 119.新型环戊烯酮衍生物由稀有放线菌南山链霉菌 NEAU 119 产生。
Nat Prod Res. 2013 Oct;27(20):1863-9. doi: 10.1080/14786419.2013.771349. Epub 2013 Feb 22.
2
Three new cyclopentenone derivatives from Actinoalloteichus nanshanensis NEAU 119.来自南山放线全壁菌NEAU 119的三种新环戊烯酮衍生物。
J Asian Nat Prod Res. 2014;16(6):587-92. doi: 10.1080/10286020.2014.921909. Epub 2014 May 27.
3
Halogenated spirotetronates from Actinoallomurus.来自小单孢菌属的卤代螺环缩酮类化合物。
J Nat Prod. 2012 Jun 22;75(6):1044-50. doi: 10.1021/np300003n. Epub 2012 May 22.
4
Isolation of C11 cyclopentenones from two didemnid species, Lissoclinum sp. and Diplosoma sp.从两个齿叶唇形藻属物种，Lissoclinum sp. 和 Diplosoma sp. 中分离 C11 环戊烯酮
Mar Drugs. 2009 Dec 17;7(4):816-32. doi: 10.3390/md7040816.
5
Daldispones A and B, two new cyclopentenones from Daldinia sp. CPCC 400770.Daldispones A 和 B，两种来自于中国被毛孢 CPCC 400770 的新的环戊烯酮。
J Antibiot (Tokyo). 2021 Mar;74(3):215-218. doi: 10.1038/s41429-020-00384-0. Epub 2020 Nov 10.
6
A Novel C21 Cyclopentenone Derivative from Cipadessa cinerascens.一种来自灰毛浆果楝的新型C21环戊烯酮衍生物。
Nat Prod Commun. 2015 Aug;10(8):1421-2.
7
Two new derivatives of griseofulvin from the mangrove endophytic fungus Nigrospora sp. (strain No. 1403) from Kandelia candel (L.) Druce.从红树林内生真菌（株号 1403）Nigrospora sp. 中分离得到的灰黄霉素的两个新衍生物。该真菌来源于海檬果（Kandelia candel（L.）Druce）。
Planta Med. 2011 Oct;77(15):1735-8. doi: 10.1055/s-0030-1271040. Epub 2011 Apr 21.
8
Cyclopentenone derivatives and polyhydroxylated steroids from the soft coral Sinularia acuta.来自尖刺软珊瑚的环戊烯酮衍生物和多羟基类固醇。
Chem Biodivers. 2015 Feb;12(2):273-83. doi: 10.1002/cbdv.201400044.
9
Palmaenones A and B, two new antimicrobial chlorinated cyclopentenones from discomycete Lachnum palmae.棕榈菌素A和B，从盘菌棕榈状毛盘菌中分离得到的两种新型抗菌氯化环戊烯酮。
Chem Pharm Bull (Tokyo). 2011;59(12):1559-61. doi: 10.1248/cpb.59.1559.
10
New cyclopentenone derivatives from an endophytic Streptomyces sp. isolated from the mangrove plant Aegiceras comiculatum.从红树植物桐花树分离出的内生链霉菌属菌株产生的新型环戊烯酮衍生物。
J Antibiot (Tokyo). 2005 Sep;58(9):594-8. doi: 10.1038/ja.2005.81.

引用本文的文献

1
Growth Promotion and Disease Suppression Ability of a sp. CB-75 from Banana Rhizosphere Soil.香蕉根际土壤中一株 sp. CB-75 的促生长及抑病能力
Front Microbiol. 2018 Jan 17;8:2704. doi: 10.3389/fmicb.2017.02704. eCollection 2017.
2
Actinoalloteichus fjordicus sp. nov. isolated from marine sponges: phenotypic, chemotaxonomic and genomic characterisation.从海洋海绵中分离出的新种峡湾放线全壁菌：表型、化学分类学和基因组特征分析
Antonie Van Leeuwenhoek. 2017 Dec;110(12):1705-1717. doi: 10.1007/s10482-017-0920-9. Epub 2017 Aug 2.
3
Screening of Rhizospheric Actinomycetes for Various In-vitro and In-vivo Plant Growth Promoting (PGP) Traits and for Agroactive Compounds.
筛选根际放线菌的各种体外和体内植物生长促进（PGP）特性及农用活性化合物。
Front Microbiol. 2016 Aug 29;7:1334. doi: 10.3389/fmicb.2016.01334. eCollection 2016.
4
A new polysubstituted cyclopentene derivative from Streptomyces sp. HS-NF-1046.一种源自链霉菌HS-NF-1046的新型多取代环戊烯衍生物。
J Antibiot (Tokyo). 2017 Feb;70(2):216-218. doi: 10.1038/ja.2016.111. Epub 2016 Sep 7.
5
Non-streptomycete actinomycetes nourish the current microbial antibiotic drug discovery.非链霉菌属放线菌为当前的微生物抗生素药物研发提供了助力。
Front Microbiol. 2013 Aug 20;4:240. doi: 10.3389/fmicb.2013.00240. eCollection 2013.