Biondi-Zoccai G, Lotrionte M, Landoni G, Modena M G
Division of Cardiology, University of Modena and Reggio Emilia, Modena, Italy ; Meta-analysis and Evidence-based medicine Training in Cardiology (METCARDIO), Ospedaletti, Italy.
HSR Proc Intensive Care Cardiovasc Anesth. 2011;3(3):161-73.
The hierarchy of evidence based medicine postulates that systematic reviews of homogenous randomized trials represent one of the uppermost levels of clinical evidence. Indeed, the current overwhelming role of systematic reviews, meta-analyses and meta-regression analyses in evidence based heath care calls for a thorough knowledge of the pros and cons of these study designs, even for the busy clinician. Despite this sore need, few succinct but thorough resources are available to guide users or would-be authors of systematic reviews. This article provides a rough guide to reading and, summarily, designing and conducting systematic reviews and meta-analyses.
循证医学的层次体系假定，对同质随机试验的系统评价代表了临床证据的最高级别之一。事实上，系统评价、荟萃分析和荟萃回归分析目前在循证医疗保健中占据着压倒性的地位，这就要求即使是忙碌的临床医生也需要全面了解这些研究设计的优缺点。尽管有这种迫切需求，但几乎没有简洁而全面的资源可用于指导系统评价的使用者或潜在作者。本文提供了一份关于阅读的简要指南，概括而言，也涉及系统评价和荟萃分析的设计与实施。
