Department of Cosmetic Science, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan.
Molecules. 2013 Feb 26;18(3):2563-70. doi: 10.3390/molecules18032563.
A new hydroxychavicol dimer, 2-(g'-hydroxychavicol)-hydroxychavicol (1), was isolated from the roots of Piper betle Linn. along with five known compounds, hydroxychavicol (2), aristololactam A II (3), aristololactam B II (4), piperolactam A (5) and cepharadione A (6). The structures of these isolated compounds were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited inhibitory effects on the generation of superoxide anion and the release of elastase by human neutrophils.
一种新的羟基胡椒酚二聚体,2-(g'-羟基胡椒酚)-羟基胡椒酚(1),从胡椒根中分离出来。与五个已知化合物,羟基胡椒酚(2),阿立洛拉他姆 A II(3),阿立洛拉他姆 B II(4),胡椒螺烷 A(5)和 Cephradione A(6)。这些分离化合物的结构通过光谱方法阐明。化合物 1 和 2 表现出对人嗜中性粒细胞中超氧阴离子生成和弹性蛋白酶释放的抑制作用。