Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
Jpn J Ophthalmol. 2013 May;57(3):308-15. doi: 10.1007/s10384-013-0232-1. Epub 2013 Feb 27.
To investigate the effects of reproducibility of optical coherence tomography (OCT) measurements and imaging alignment on predictive performance for visual outcome following macular hole (MH) surgery.
We retrospectively reviewed 50 eyes that underwent MH surgery. Preoperative cross-sectional images through the center of the MH (on-center image) and through an off-center point (off-center image) were obtained from the OCT data. In each image, the following OCT parameters were either measured or calculated: minimum diameter, base diameter, hole height, temporal and nasal arm length, photoreceptor inner segment/outer segment (IS/OS) defect length, the hole form factor, the macular hole index and the tractional hole index. The IS/OS defect area was also measured.
The reproducibility of OCT parameter values was moderate to high, and there was a significant difference in the mean measurement values between the on- and off-center images. Predictive values varied between sessions and raters, and only the preoperative photoreceptor IS/OS defect length consistently showed significant correlation with postoperative visual outcome.
Both the reproducibility and imaging alignment might affect the predictive performance of the OCT parameter for postoperative visual outcome following MH surgery. The preoperative photoreceptor IS/OS defect length seems to be the most useful parameter in this regard.
研究光学相干断层扫描（OCT）测量的可重复性和成像对准对黄斑裂孔（MH）手术后视力预测结果的影响。
我们回顾性分析了 50 只接受 MH 手术的眼。从 OCT 数据中获取 MH 中心的横截面图像（中心图像）和偏心点的横截面图像（偏心图像）。在每张图像中，测量或计算了以下 OCT 参数：最小直径、基底直径、孔高、颞侧和鼻侧臂长度、光感受器内节/外节（IS/OS）缺损长度、孔形态因子、黄斑孔指数和牵拉性孔指数。还测量了 IS/OS 缺损面积。
OCT 参数值的可重复性为中等至高，中心和偏心图像之间的平均测量值存在显著差异。预测值在各次检查和评分者之间存在差异，只有术前光感受器 IS/OS 缺损长度与术后视力结果始终显示出显著相关性。
OCT 测量值的可重复性和成像对准都可能影响 MH 手术后视力的 OCT 参数预测性能。在这方面，术前光感受器 IS/OS 缺损长度似乎是最有用的参数。
