中医：治疗老年痴呆症的有前景的候选者。
Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer's disease.
机构信息
Department of Neurology, Henan Provincial People's Hospital, 450003, Zhengzhou, Henan Province, People's Republic of China.
Department of Neurology and Institute of Neurology, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, 200025, Shanghai, People's Republic of China.
出版信息
Transl Neurodegener. 2013 Feb 28;2(1):6. doi: 10.1186/2047-9158-2-6.
Abstract
Alzheimer's disease (AD) is an age-related neurodegenerative disorder, characterized clinically by insidious onset of memory and cognition impairment, emergence of psychiatric symptoms and behavioral disorder, and impairment of activities of daily living (ADL). Traditional Chinese medicine (TCM) is practiced in the Chinese health care system for more than 2,000 years. In recent years, scientists have isolated many novel compounds from herbs, some of which improve dementia with fewer side effects than conventional drugs and are regarded as potential anti-AD drugs. In this review, we summarize the latest research progress on TCM showing their possible role of treatment of AD and other demented diseases and possible pharmacological actions.
摘要
阿尔茨海默病（AD）是一种与年龄相关的神经退行性疾病，临床上以隐匿性记忆和认知障碍、精神症状和行为障碍的出现以及日常生活活动（ADL）能力的损害为特征。中医药在中国医疗体系中已有 2000 多年的历史。近年来，科学家们从草药中分离出许多新型化合物，其中一些改善痴呆的药物比传统药物副作用更少，被认为是有潜力的抗 AD 药物。在这篇综述中，我们总结了中医药治疗 AD 和其他痴呆疾病的最新研究进展及其可能的药理作用。
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